2695-47-8 Usage
Description
6-Bromo-1-hexene is a colorless liquid that is known for its unique chemical properties. It is an organic compound with the molecular formula C6H11Br, which consists of a hexene chain with a bromine atom attached to the sixth carbon. 6-Bromo-1-hexene has been widely studied for its various applications in the chemical industry, particularly in the synthesis of other compounds.
Uses
Used in Chemical Synthesis:
6-Bromo-1-hexene is used as a key intermediate in the chemical synthesis of various compounds. Its ability to form Grignard compounds upon reaction with magnesium has been extensively investigated, making it a valuable starting material for the preparation of a range of organic molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 6-Bromo-1-hexene is used as a precursor for the preparation of epoxides, such as 6-bromo-1,2-epoxyhexane. These epoxides are important intermediates in the synthesis of various pharmaceutical compounds, including those with potential therapeutic applications.
Used in Material Science:
6-Bromo-1-hexene is also utilized in the preparation of 4-alkenylbenzonitriles, which are important building blocks for the synthesis of polymers and other materials with specific properties. The simple and direct preparation of these compounds using anionic reduced forms of terephthalonitrile in liquid ammonia has been demonstrated, highlighting the versatility of 6-Bromo-1-hexene in material science applications.
Used in Surface Chemistry Studies:
The thermal chemistry of 6-bromo-1-hexene on Ni (100) surface has been studied under ultrahigh vacuum conditions using X-ray photoelectron spectroscopy and temperature-programmed desorption. These studies contribute to the understanding of the interaction between 6-Bromo-1-hexene and metal surfaces, which is crucial for various applications in catalysis and surface modification.
Synthesis Reference(s)
Synthesis, p. 885, 1984 DOI: 10.1055/s-1984-31010
Check Digit Verification of cas no
The CAS Registry Mumber 2695-47-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,6,9 and 5 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 2695-47:
(6*2)+(5*6)+(4*9)+(3*5)+(2*4)+(1*7)=108
108 % 10 = 8
So 2695-47-8 is a valid CAS Registry Number.
InChI:InChI=1/C6H11Br/c1-2-3-4-5-6-7/h2H,1,3-6H2
2695-47-8Relevant articles and documents
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Bodewitz,H.W.H.J. et al.
, p. 1053 - 1063 (1975)
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A useful modification of the Kraus procedure1 for preparation of ω-bromo-1-alkenes by HMPA-promoted elimination of HBR from 1,ω-dibromoalkanes
Hoye,Van Veidhuizen,Vos,Zhao
, p. 1367 - 1371 (2001)
A reliable, reproducible, general, and detailed procedure for the mono-elimination of hydrogen bromide from 1,ω-dibromoalkanes is described.
Mechanistic Insights into FLP-Catalyzed Iodoperfluoroalkylations
Spittler, Michael,Helmecke, Lucas,Czekelius, Constantin
supporting information, p. 458 - 468 (2018/09/06)
The frustrated Lewis pair-catalyzed iodoperfluoroalkylation of olefins, its substrate activation mode, and catalyst degradation pathways are mechanistically investigated by kinetic measurements. The transformation most likely proceeds via coordination of the phosphane to the perfluoroalkyl iodide and involves radical intermediates.
Aromatic Claisen Rearrangements of Benzyl Ketene Acetals: Conversion of Benzylic Alcohols to (ortho-Tolyl)acetates
Burns, Jed M.,Krenske, Elizabeth H.,McGeary, Ross P.
supporting information, p. 252 - 256 (2017/01/24)
Claisen rearrangements of benzyl vinyl ethers are much less facile than those of aliphatic allyl vinyl ethers, and their synthetic utility has remained relatively unexplored. A one-pot procedure is reported for the generation and Claisen rearrangement of benzyl vinyl ethers that contain an activating α-alkoxy substituent on the vinyl group. A [3,3]-sigmatropic mechanism was supported by trapping of the intermediate isotoluene in an intramolecular Alder–ene reaction.