26974-36-7

Basic information

• Product Name: benzenethiosulfonic acid S-(4-bromophenyl) ester
• Synonyms: benzenethiosulfonic acid S-(4-bromophenyl) ester
• CAS NO: 26974-36-7
• Molecular Weight: 329.238
• Mol File: 26974-36-7.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: benzenethiosulfonic acid S-(4-bromophenyl) ester(CAS DataBase Reference)
• NIST Chemistry Reference: benzenethiosulfonic acid S-(4-bromophenyl) ester(26974-36-7)
• EPA Substance Registry System: benzenethiosulfonic acid S-(4-bromophenyl) ester(26974-36-7)

Safety Data

• Hazardous Substances Data: 26974-36-7(Hazardous Substances Data)

Upstream product

• 5335-84-2 bis(4-bromophenyl)disulfide 
• 873-55-2 sodium benzenesulfonate 
• 106-53-6 para-bromobenzenethiol 
• 80-17-1 benzenesufonyl hydrazide 
• 532-32-1 sodium benzoate 
• 1887-29-2 sodium phenylthiosulfonate 
• 369-57-3 benzenediazonium tetrafluoroborate 

Downstream Products

• 635695-44-2 1-bromo-4-[(4-imethoxybenzyl)thio]benzene 

Relevant articles and documents

Preparation method of thiosulfonate compound

The invention belongs to the field of organic synthetic chemistry, and particularly discloses a preparation method of a thiosulfonate compound. The specific preparation process comprises the following steps: taking aryl diazonium salt, sodium pyrosulfite and thiophenol/mercaptan as raw materials, taking organic dye as a photocatalyst, adding an organic solvent, and reacting for 12 hours at room temperature under the irradiation of an LED visible light lamp and nitrogen protection to generate thiosulfonate; and after the reaction is finished, adding distilled water into the reaction system, extracting the reaction liquid with ethyl acetate, concentrating the extraction liquid to obtain a crude product, and carrying out silica gel column chromatography separation on the crude product to obtain thiosulfonate. According to the method, simple and easily available sodium pyrosulfite is used as a sulfone source, cheap organic dye is used as a photocatalyst, clean light energy is used as a reaction energy source, a high-energy-consumption heating device and a metal catalyst or strong acid are not used, the reaction condition is mild, the operation is simple and convenient, and a green synthesis strategy is provided for thiosulfonate.

Visible-Light-Induced Cyclization/Aromatization of 2-Vinyloxy Arylalkynes: Synthesis of Thio-Substituted Dibenzofuran Derivatives

A visible-light-induced cascade reaction of 2-vinyloxy arylalkynes with thiosulfonates was developed and provided unexpected thio-substituted dibenzofuran derivatives in moderate yields. Mechanistic studies revealed the thiosulfonylation product of 2-vinyloxy arylalkyne was the key intermediate, and the additive disulfide played the role of hydrogen abstraction in the aromatization process to offer the desired product. This reaction presents a new reaction mode for the construction of polycyclic oxygen heterocycles.

Nickel-Catalyzed Defluorinative Reductive Cross-Coupling Reaction of gem-Difluoroalkenes with Thiosulfonate or Selenium Sulfonate

A nickel-catalyzed defluorinative reductive cross-coupling of gem-difluoroalkenes with thiosulfonate or selenosulfonates is described. The reaction involves the formation of thiolated or selenylated monofluoroolefins via regioselective C-F bond cleavage and C-S or C-Se bond formation and features easily available substrates, mild reaction conditions, and high E-selectivity. One of the derivatives by further cross coupling with PhMgBr exhibited an aggregation-induced emission enhancement effect.