27023-05-8 Usage
Description
Methyl 4-hydroxy-2,5-dimethylbenzoate is an organic compound that serves as a crucial reagent in the synthesis of various chemical compounds. It is characterized by its molecular structure, which includes a benzene ring with a methyl ester group, a hydroxyl group, and two methyl groups at specific positions. Methyl 4-hydroxy-2,5-diMethylbenzoate plays a significant role in the pharmaceutical and chemical industries due to its ability to facilitate the creation of important molecules.
Uses
Used in Pharmaceutical Industry:
Methyl 4-hydroxy-2,5-dimethylbenzoate is used as a reagent for the synthesis of N-Benzoyl-2-methylindole-3-acetic Acids. These synthesized compounds are known as prostaglandin (PG) D2 receptor antagonists, which have potential applications in the treatment of various medical conditions. The antagonists can modulate the activity of the PGD2 receptor, which is involved in several physiological processes, including inflammation, pain, and allergic responses.
In the synthesis process, Methyl 4-hydroxy-2,5-dimethylbenzoate acts as a key building block, providing the necessary structural elements for the formation of the final product. Its presence in the reaction mixture ensures the successful creation of the desired N-Benzoyl-2-methylindole-3-acetic Acids, which can then be further studied and developed for their potential therapeutic uses.
The use of Methyl 4-hydroxy-2,5-dimethylbenzoate in the pharmaceutical industry highlights its importance as a versatile and valuable reagent. Its ability to contribute to the synthesis of biologically active compounds makes it a valuable asset in the development of new drugs and therapies for various medical conditions. As research continues to explore the potential applications of this compound, it is likely that Methyl 4-hydroxy-2,5-dimethylbenzoate will play an increasingly significant role in the advancement of pharmaceutical science.
Check Digit Verification of cas no
The CAS Registry Mumber 27023-05-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,7,0,2 and 3 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 27023-05:
(7*2)+(6*7)+(5*0)+(4*2)+(3*3)+(2*0)+(1*5)=78
78 % 10 = 8
So 27023-05-8 is a valid CAS Registry Number.
27023-05-8Relevant articles and documents
Computational and Experimental Studies of Phthaloyl Peroxide-Mediated Hydroxylation of Arenes Yield a More Reactive Derivative, 4,5-Dichlorophthaloyl Peroxide
Camelio, Andrew M.,Liang, Yong,Eliasen, Anders M.,Johnson, Trevor C.,Yuan, Changxia,Schuppe, Alex W.,Houk,Siegel, Dionicio
, p. 8084 - 8095 (2015/09/01)
The oxidation of arenes by the reagent phthaloyl peroxide provides a new method for the synthesis of phenols. A new, more reactive arene oxidizing reagent, 4,5-dichlorophthaloyl peroxide, computationally predicted and experimentally determined to possess enhanced reactivity, has expanded the scope of the reaction while maintaining a high level of tolerance for diverse functional groups. The reaction proceeds through a novel "reverse-rebound" mechanism with diradical intermediates. Mechanistic insight was achieved through isolation and characterization of minor byproducts, determination of linear free energy correlations, and computational analysis of substituent effects of arenes, each of which provided additional support for the reaction proceeding through the diradical pathway.
AMINO ALCOHOL DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME, AND USE THEREOF
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Page/Page column 28-29, (2008/06/13)
The present invention provides compounds represented by general formula (I): or pharmaceutical acceptable salts thereof, wherein R1 and R2 are each hydrogen or lower alkyl; R3 R4, R5 and R6 are each hydrogen, halogen, lower alkyl or lower alkoxy; R7 and R8 are each hydrogen, halogen, lower alkyl, halo-lower alkyl, lower alkoxy, cycloalkyl, aryl, heteroaryl, cyano, a hydroxyl group, lower acyl, carboxy or the like; R9 is -C(O)-R10, -A1-C(O)-R10, -O-A2-C(O)-R10 or a tetrazol-5-yl group, which exhibit potent and selective β3-adrenoceptor stimulating activities. The present invention also provides pharmaceutical compositions containing said compound, and uses thereof.
