27025-39-4Relevant articles and documents
A New Synthesis of Peptides from Azides and Unactivated Carboxylic Acids
Zaloom, Jeffrey,Calandra, Michael,Roberts, David C.
, p. 2601 - 2603 (2007/10/02)
The title reaction, in which an azido compound is treated first with a tertiary phosphine, followed by warming in an inert solvent with a carboxylic acid, has been used to synthesize a number of small peptides and appears from mechanistic studies to proceed via a pentacoordinate phosphorus intermediate.