27038-10-4

Basic information

• Product Name: N-Acetyl-α-<(E)-styryl>glycine
• CAS NO: 27038-10-4
• Molecular Weight: 219.24
• Mol File: 27038-10-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-Acetyl-α-<(E)-styryl>glycine(CAS DataBase Reference)
• NIST Chemistry Reference: N-Acetyl-α-<(E)-styryl>glycine(27038-10-4)
• EPA Substance Registry System: N-Acetyl-α-<(E)-styryl>glycine(27038-10-4)

Safety Data

• Hazardous Substances Data: 27038-10-4(Hazardous Substances Data)

Upstream product

• 54681-67-3 2-acetamido-3-ethoxy-3-oxopropanoic acid 
• 7422-28-8 (E)-2-phenylethenyl(trimethyl)stannane 
• 60-35-5 acetamide 
• 710-11-2 2-oxo-4-phenylbutyric acid 
• 162247-73-6 2-Methyl-5-oxo-4-((E)-styryl)-4,5-dihydro-oxazole-4-carboxylic acid ethyl ester 
• 162247-62-3 4-Ethoxycarbonyl-2-methyl-4,5-dihydro-1,3-oxazol-5-one 
• 122507-69-1 (E)-styryl-lead triacetate 

Relevant articles and documents

Reaction of organolead triacetates with 4-ethoxycarbonyl-2-methyl-4,5-dihydro-1,3-oxazol-5-one. The synthesis of α-aryl- and α-vinyl-N-acetylglycines and their ethyl esters and their enzymic resolution

4-Ethoxycarbonyl-2-methyl-4,5-dihydro-1,3-oxazol-5-one 7, which may be readily obtained from diethyl acetamidomalonate, undergoes high-yielding arylation and vinylation at the 4-position with organolead triacetates to give compounds which may be hydrolysed to give either the α-aryl- or α-vinyl-N-acetylglycine or the corresponding ethyl ester. The kinetic resolution of a number of these derivatives by enzymic hydrolysis of either the amide or ester function has been demonstrated.