27069-81-4

Basic information

• Product Name: diethyl N-(4-{[(2-amino-4-oxo-1,4-dihydroquinazolin-6-yl)methyl]amino}benzoyl)glutamate
• Synonyms: diethyl N-(4-{[(2-amino-4-hydroxyquinazolin-6-yl)methyl]amino}benzoyl)glutamate; glutamic acid, N-[4-[[(2-amino-4-hydroxy-6-quinazolinyl)methyl]amino]benzoyl]-, diethyl ester
• CAS NO: 27069-81-4
• Molecular Formula: C₂₅H₂₉N₅O₆
• Molecular Weight: 495.5277
• Mol File: 27069-81-4.mol
• Article Data: 2

Chemical Properties

• Density: 1.35g/cm³
• Refractive Index: 1.631
• CAS DataBase Reference: diethyl N-(4-{[(2-amino-4-oxo-1,4-dihydroquinazolin-6-yl)methyl]amino}benzoyl)glutamate(CAS DataBase Reference)
• NIST Chemistry Reference: diethyl N-(4-{[(2-amino-4-oxo-1,4-dihydroquinazolin-6-yl)methyl]amino}benzoyl)glutamate(27069-81-4)
• EPA Substance Registry System: diethyl N-(4-{[(2-amino-4-oxo-1,4-dihydroquinazolin-6-yl)methyl]amino}benzoyl)glutamate(27069-81-4)

Safety Data

• Hazardous Substances Data: 27069-81-4(Hazardous Substances Data)

Usage

General Description

Diethyl N-(4-{[(2-amino-4-oxo-1,4-dihydroquinazolin-6-yl)methyl]amino}benzoyl)glutamate is a compound with a complex chemical structure. It consists of a diethyl ester group, a benzoyl group, a glutamate group, and a quinazolin-6-ylmethyl group, all connected by an amide linkage. diethyl N-(4-{[(2-amino-4-oxo-1,4-dihydroquinazolin-6-yl)methyl]amino}benzoyl)glutamate is a potential drug candidate, as it contains an amino group that could potentially interact with a target protein or enzyme in the body. However, further research is required to understand its biological activity and potential therapeutic applications.

Upstream product

• 13726-52-8 diethyl N-(p-aminobenzoyl)-L-glutamate 

Downstream Products

• 80015-08-3 diethyl N-<4--N-(cyanomethyl)amino>benzoyl>-L-glutamate 
• 76858-74-7 2-{4-[(2-Amino-4-hydroxy-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid diethyl ester 
• 76849-19-9 10-propargyl-5,8-dideazafolate 
• 80015-09-4 N-<4--N-(cyanomethyl)amino>benzoyl>-L-glutamic acid 
• 80014-95-5 (S)-2-{4-[(2-Amino-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-carbamoylmethyl-amino]-benzoylamino}-pentanedioic acid 
• 80015-08-3 diethyl N-(4-(N-((2-amino-4-hydroxy-6-quinazolinyl)methyl)cyanomethylamino)benzoyl)-L-glutamate 

Relevant articles and documents

Synthesis of 10-Acetyl-5,8-dideazafolic Acid: A Potent Inhibitor of Glycinamide Ribonucleotide Transformylase

10-Acetyl-5,8-dideazafolic acid has been synthesized in good yield from the parent compound, 5,8-dideazafolic acid.This quinazoline folate analogue showed no activity as a substrate for the folate-requiring de novo purine biosynthetic enzyme glycinamide r