2709-56-0 Usage
Description
Flupentiol, also known as Flupentixol, is a thioxanthene derivative with a trifluoromethyl substituent at the 2-position and a 3-(4-(2-hydroxyethyl)piperazin-1-yl)propylidene group at the 10-position. It has undefined double bond stereochemistry and is primarily used in the pharmaceutical industry due to its various applications.
Uses
Used in Pharmaceutical Industry:
Flupentiol is used as an antipsychotic agent for the treatment of various psychiatric disorders, such as schizophrenia and bipolar disorder. It helps in managing symptoms like hallucinations, delusions, and agitation by blocking the action of dopamine in the brain.
Used in Neurochemistry Research:
Flupentiol is utilized as a research tool in neurochemistry to study the effects of dopamine receptor antagonists. Its ability to block dopamine receptors makes it a valuable compound for understanding the role of dopamine in various brain functions and disorders.
Used in Animal Health:
In the veterinary field, Flupentiol is used as a tranquilizer and sedative for animals, particularly in the management of aggressive or anxious behavior in pets. It helps in calming the animals without causing significant sedation, making it a preferred choice for certain applications.
Therapeutic Function
Tranquilizer
Check Digit Verification of cas no
The CAS Registry Mumber 2709-56-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,7,0 and 9 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 2709-56:
(6*2)+(5*7)+(4*0)+(3*9)+(2*5)+(1*6)=90
90 % 10 = 0
So 2709-56-0 is a valid CAS Registry Number.
InChI:InChI=1/C23H27F3N2OS/c24-23(25,26)17-7-8-22-20(16-17)18(19-4-1-2-6-21(19)30-22)5-3-9-27-10-12-28(13-11-27)14-15-29/h1-2,4-8,16,20,22,29H,3,9-15H2
2709-56-0Relevant articles and documents
A hydrochloric acid flupentixol preparation method
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Paragraph 0032-0037, (2020/02/08)
The invention provides a preparation method of flupentixol dihydrochloride, which comprises the following steps: reacting and dehydrating 10-hydroxy-10-(3-dimethylaminopropyl)-2-trifluoromethyl thioxanthene and sulfoxide chloride or acetic anhydride to prepare high-content Z-type 10-[3-(EZ)-dimethylaminopropyl]-2-trifluoromethyl thioxanthene, reacting with N-hydroxyethyl piperazidine to prepare flupentixol base, and finally, introducing sufficient hydrochloric acid gas into the flupentixol base to prepare the high-content Z-type flupentixol dihydrochloride. The method has the advantages of fewer steps, high yield and high product purity, is simple to operate, and does not use any extremely toxic substance to pollute the environment. The Z-type flupentixol dihydrochloride content in the flupentixol dihydrochloride prepared by the method is 42-52%, and conforms to the quality standard specification for flupentixol dihydrochloride in European Pharmacopoeia.
PROCESS FOR THE PREPARATION OF Z-FLUPENTIXOL
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Page/Page column 10-11, (2010/02/11)
The present invention relates to a process for the separation of flupentixol isomers, particularly, a process for the preparation of Z-flupentixol and the decanoate ester and novel synthetic intermediates thereof.