271260-82-3

Basic information

• Product Name: (S)-2-(N-tert-butoxycarbonylamino)-3-butenyl-acetate
• Synonyms: (S)-2-(N-tert-butoxycarbonylamino)-3-butenyl-acetate
• CAS NO: 271260-82-3
• Molecular Weight: 229.276
• Mol File: 271260-82-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (S)-2-(N-tert-butoxycarbonylamino)-3-butenyl-acetate(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-(N-tert-butoxycarbonylamino)-3-butenyl-acetate(271260-82-3)
• EPA Substance Registry System: (S)-2-(N-tert-butoxycarbonylamino)-3-butenyl-acetate(271260-82-3)

Safety Data

• Hazardous Substances Data: 271260-82-3(Hazardous Substances Data)

Upstream product

• 108-22-5 Isopropenyl acetate 
• 169324-82-7 N-tert-butoxycarbonyl-N-(1-hydroxymethyl-2-propenyl)amine 

Downstream Products

• 133625-87-3 tert-butyl (4S)-2,2-dimethyl-4-vinyl-1,3-oxazolidine-3-carboxylate 
• 917365-73-2 C₃₄H₃₅BrN₄O₁₀S₂ 
• 917365-70-9 C₃₆H₃₉BrN₄O₁₀S₂ 
• 917365-57-2 C₂₆H₂₉BrN₂O₆S 
• 91103-37-6 tert-butyl [(1S)-1-(hydroxymethyl)prop-2-en-1-yl]carbamate 

Relevant articles and documents

Synthesis of unnatural amino acids via suzuki cross-coupling of enantiopure vinyloxazolidine derivatives

(R and S)-α-Amino alcohols and α-amino acids, including 4-methoxyhomophenylalanine, with a variety of unnatural side chains have been synthesized via palladium-catalyzed cross-coupling Suzuki reactions. The key building blocks 1 and 2, synthesized from the common achiral precursor 2-butene-1,4-diol, were made enantiopure utilizing a Pseudomonas cepacia lipase-catalyzed kinetic resolution. The optimal conditions for the Suzuki cross-coupling and the subsequent oxidations of the resultant α-amino alcohols are described.