27130-46-7 Usage
Description
O-Benzoyl-N-methylhydroxylamine Hydrochloride is an organic compound that serves as a versatile reagent in various chemical reactions. It is characterized by its ability to facilitate benzoylation and a-oxygenation processes, making it a valuable tool in synthetic chemistry.
Uses
Used in Chemical Synthesis:
O-Benzoyl-N-methylhydroxylamine Hydrochloride is used as a benzoylation reagent for the a-oxygenation of aldehydes and ketones. It aids in the formation of various chemical intermediates and final products by introducing a benzoyl group to the molecule.
Used in NHC-catalyzed Redox Esterification and Cycloaddition Reactions:
In this application, O-Benzoyl-N-methylhydroxylamine Hydrochloride acts as a key reactant, enabling the efficient conversion of starting materials into ester and cyclic products under the catalysis of N-heterocyclic carbenes (NHCs).
Used in Pd/pyrrolidine-catalyzed Tsuji-Trost Cyclization of Aldehydes:
O-Benzoyl-N-methylhydroxylamine Hydrochloride is utilized as a reactant in the palladium and pyrrolidine-catalyzed version of the Tsuji-Trost reaction, which is a powerful method for the cyclization of aldehydes to form complex molecular structures.
Used in the Synthesis of α-acyloxy Ketones via Oxyacylation Reaction:
O-Benzoyl-N-methylhydroxylamine Hydrochloride is employed in the preparation of α-acyloxy ketones through an oxyacylation reaction, which is an important synthetic strategy for constructing carbonyl-containing molecules with additional oxygen-containing functional groups.
Check Digit Verification of cas no
The CAS Registry Mumber 27130-46-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,7,1,3 and 0 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 27130-46:
(7*2)+(6*7)+(5*1)+(4*3)+(3*0)+(2*4)+(1*6)=87
87 % 10 = 7
So 27130-46-7 is a valid CAS Registry Number.
InChI:InChI=1/C8H9NO2.ClH/c1-9-11-8(10)7-5-3-2-4-6-7;/h2-6,9H,1H3;1H
27130-46-7Relevant articles and documents
A practical procedure for carbonyl -Oxidation: Synthesis of (2-benzoyloxy)-1,4-cyclohexanedione mono-ethylene ketal
Jones, Teyrnon C.,Tomkinson, Nicholas C. O.,Patil, Kalyani,Wipf, Peter
, p. 233 - 241 (2017/09/30)
-
Direct O-Acylation of Hydroxylamine and N-Monosubstituted Hydroxylamines by 1-Benzoylimidazole
Geffken, Detlef
, p. 744 - 746 (2007/10/02)
Under suitable conditions 1-benzoylimidazole (2) reacts with hydroxylamines 3 to give O-benzoylhydroxylamines 4, which are isolated as their hydrochlorides 5 in 55-83percent yields.
