27330-27-4Relevant articles and documents
MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF
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Paragraph 00135; 00136; 00137, (2016/09/22)
Provided are novel compounds of Formula (I): and pharmaceutically acceptable salts thereof, which are useful for treating a variety of diseases, disorders or conditions, associated with methyl modifying enzymes. Also provided are pharmaceutical compositions comprising the novel compounds of Formula (I), pharmaceutically acceptable salts thereof, and methods for their use in treating one or more diseases, disorders or conditions, associated with methyl modifying enzymes.
Studies on 1-Alkyl-2(1H)-pyridone Derivatives. XXXI. Syntheses of Isoquinoline Derivatives Using Diels-Alder Reaction of 4-Acetyl-, 4-Cyano-, and 4-Methoxycarbonyl-1-methyl-2(1H)-pyridones with 1,3-Butadiene Derivatives
Tomisawa, Hiroshi,Fujita, Reiko,Kato, Hideki,Hayasaka, Kazuhiko,Kamimura, Taiki,Hongo, Hiroshi
, p. 1882 - 1885 (2007/10/02)
The Diels-Alder reaction of 4-cyano-, 4-methoxycarbonyl-, and 4-acetyl-2(1H)-pyridones (I, II, and IV) with 1,3-butadiene derivatives (III and V) were carried out to give 4a-substituted tetrahydro-1(2H)-isoquinolone derivatives (VI-IX, XV, XIX, and XX).