2735-21-9

Basic information

• Product Name: (3E,5alpha)-N-hydroxycholestan-3-imine
• CAS NO: 2735-21-9
• Molecular Formula: C₂₇H₄₇NO
• Molecular Weight: 401.6682
• Mol File: 2735-21-9.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 497.318°C at 760 mmHg
• Flash Point: 331.295°C
• Density: 1.112g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.583
• CAS DataBase Reference: (3E,5alpha)-N-hydroxycholestan-3-imine(CAS DataBase Reference)
• NIST Chemistry Reference: (3E,5alpha)-N-hydroxycholestan-3-imine(2735-21-9)
• EPA Substance Registry System: (3E,5alpha)-N-hydroxycholestan-3-imine(2735-21-9)

Safety Data

• Hazardous Substances Data: 2735-21-9(Hazardous Substances Data)

Usage

Description

(3E,5alpha)-N-hydroxycholestan-3-imine is a chemical compound belonging to the class of imines, characterized by the presence of a carbon-nitrogen double bond. It is derived from cholestan, a steroidal compound found in animal fats, and its (3E,5alpha) designation indicates the specific stereochemistry of the compound. (3E,5alpha)-N-hydroxycholestan-3-imine has been studied for its potential biological activities, including its role in lipid metabolism and its potential as a pharmaceutical agent. Its structure and properties make it an interesting target for further research in the fields of chemistry and medicine.

Uses

Used in Pharmaceutical Industry:
(3E,5alpha)-N-hydroxycholestan-3-imine is used as a pharmaceutical agent for its potential role in lipid metabolism. Its unique structure and properties make it a promising candidate for the development of new drugs targeting lipid-related disorders and conditions.
Used in Chemical Research:
(3E,5alpha)-N-hydroxycholestan-3-imine is used as a subject of study in chemical research to explore its properties, reactivity, and potential applications in various chemical processes. Its unique structure and the presence of a carbon-nitrogen double bond make it an interesting compound for further investigation and development.

Upstream product

• 566-88-1 dihydrocholesterone 
• 80-97-7 Cholestanol 

Downstream Products

• 2206-20-4 3α-amino-5α-cholestane 
• 2206-21-5 3β-amino-5α-cholestane 
• 15600-08-5 cholestan-3-one 
• 1253-90-3 5α-cholestan-3β-yldimethylamine 
• 1912-64-7 3β-(acetylamino)-5α-cholestane 

Relevant articles and documents

A hybrid molecule of a GFP chromophore analogue and cholestene as a viscosity-dependent and cholesterol-responsive fluorescent sensor

Diarylmethylenated and cholestene (or -tane)-hybrid analogues of the GFP chromophore, namely, Ch-DAINs were successfully synthesised by a condensation reaction between methyl imidates and N-(diarylmethylene)glycinates. Among the Ch-DAINs synthesised, a diphenyl-type analogue showed viscosity-dependent and cholesterol-responsive fluorescent properties. It showed a nearly linear increase of the fluorescence emission in triglycerides and vesicles as the amount of cholesterol was increased.

Resolution of conflicting migratory reports in ring expansion of 3-keto steroids to oxygen and nitrogen

The migration of C-2 and/or C-4 to O or N in the Beckmann, Schmidt, and Baeyer-Villiger reactions of 3-keto steroids has been studied with the aid of (13)Cmr spectroscopy.Authentic specimens of the eight possible lactone and lactam products from both 5α- and 5β-cholestan-3-one have been prepared; their physical properties and 13Cmr assignments are given.Seven ring expansion reactions reported to give only one product have been found to give both possible migration products.The much studied reactions of 5α-cholestan-3,6-dione and its derivatives have been reexamined.The results emphasize again the necessity of using 13C spectra both as an analytical tool and as the best criterion of purity in work with these molecules.