27418-59-3

Basic information

• Product Name: 3-P-TOLYLAMINO-PROPIONIC ACID
• Synonyms: b-Alanine, N-p-tolyl- (8CI);3-p-Toluidinopropionic acid; N-p-Tolyl-b-alanine
• CAS NO: 27418-59-3
• Molecular Formula: C₁₀H₁₃NO₂
• Molecular Weight: 179.22
• Mol File: 27418-59-3.mol
• Article Data: 2

Chemical Properties

• Melting Point: 42 °C
• Boiling Point: 368.2°C at 760 mmHg
• Flash Point: 176.5°C
• Appearance: /
• Density: 1.172±0.06 g/cm3(Predicted)
• Vapor Pressure: 4.51E-06mmHg at 25°C
• PKA: 3.59±0.12(Predicted)
• CAS DataBase Reference: 3-P-TOLYLAMINO-PROPIONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3-P-TOLYLAMINO-PROPIONIC ACID(27418-59-3)
• EPA Substance Registry System: 3-P-TOLYLAMINO-PROPIONIC ACID(27418-59-3)

Safety Data

• Hazardous Substances Data: 27418-59-3(Hazardous Substances Data)

Usage

InChI:InChI=1/C10H13NO2/c1-8-2-4-9(5-3-8)11-7-6-10(12)13/h2-5,11H,6-7H2,1H3,(H,12,13)/p-1

Upstream product

• 141-76-4 3-iodopropanoic acid 
• 106-49-0 p-toluidine 
• 57-57-8 β-Propiolactone 
• 7732-18-5 water 
• 1077-24-3 3-(p-tolylamino)propionitrile 
• 207454-11-3 3-p-tolylaminopropionic acid ethyl ester 

Downstream Products

• 855946-35-9 N-chlorocarbonyl-N-p-tolyl-β-alanine 
• 106-49-0 p-toluidine 
• 79-10-7 acrylic acid 
• 36054-00-9 6-methyl-2,3-dihydroquinolin-4(1H)-one 
• 21911-86-4 3-[(4-methylphenyl)amino]propanehydrazide 
• 1410133-69-5 3-[(4-methylphenyl)(phenylcarbamoyl)amino]-N-[(phenylcarbamoyl)amino]propanamide 
• 1410133-73-1 3-[(4-methylphenyl)(phenylcarbamothioyl)amino]-N-[(phenylcarbamothioyl)amino]propanamide 
• 1410133-76-4 3-[(4-methylphenyl)[(4-methylphenyl)carbamothioyl]amino]-N-[[(4-methylphenyl)carbamothioyl]amino]propanamide 
• 1410133-78-6 2,4-dihydro-5-[2-[(4-methylphenyl)amino]ethyl]-4-phenyl-3H-1,2,4-triazol-3-one 
• 1410133-82-2 4-(3,5-dimethylphenyl)-2,4-dihydro-5-[2-[(4-methylphenyl)amino]ethyl]-3H-1,2,4-triazol-3-one 
• 1410133-83-3 2,4-dihydro-5-[2-[(4-methylphenyl)amino]ethyl]-4-phenyl-3H-1,2,4-triazole-3-thione 
• 1410133-86-6 2,4-dihydro-4-(4-methylphenyl)-5-[2-[(4-methylphenyl)-amino]ethyl]-3H-1,2,4-triazole-3-thione 
• 1410133-89-9 3-(4-methylphenyl)-1-phenyl-3-[2-[5-(phenylamino)-1,3,4-oxadiazol-2-yl]ethyl]urea 
• 1410133-90-2 3-(4-methylphenyl)-1-phenyl-3-[2-[5-(phenylamino)-1,3,4-thiadiazol-2-yl]ethyl]thiourea 

Relevant articles and documents

Quinolinoneacetic acid derivatives as novel glutathione S-transferase P1-1 inhibitors: Insights into the interaction modes by molecular modeling

Glutathione S-transferase P1-1 (GSTP1-1, EC 2.5.1.18) is generally conceived to be an important player in the acquired resistance of tumor to anticancer agents, thus a series of quinolinoneacetic acid derivatives were synthesized and their inhibitory effe