274264-01-6

Basic information

• Product Name: 6-methyl-2-(4'-bromophenyl)imidazo[1,2-a]pyridine-3-acetonitrile
• Synonyms: 6-methyl-2-(4'-bromophenyl)imidazo[1,2-a]pyridine-3-acetonitrile
• CAS NO: 274264-01-6
• Molecular Weight: 326.195
• Mol File: 274264-01-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 6-methyl-2-(4'-bromophenyl)imidazo[1,2-a]pyridine-3-acetonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 6-methyl-2-(4'-bromophenyl)imidazo[1,2-a]pyridine-3-acetonitrile(274264-01-6)
• EPA Substance Registry System: 6-methyl-2-(4'-bromophenyl)imidazo[1,2-a]pyridine-3-acetonitrile(274264-01-6)

Safety Data

• Hazardous Substances Data: 274264-01-6(Hazardous Substances Data)

Upstream product

• 274263-97-7 6-methyl-2-(4'-bromophenyl)-3-dimethylaminomethylimidazo[1,2-a]pyridine 
• 1023-01-4 6-methyl-2-(4'-bromophenyl)imidazo[1,2-a]pyridine 
• 151-50-8 potassium cyanide 

Downstream Products

• 274264-03-8 6-methyl-2-(4'-bromophenyl)imidazo[1,2-a]pyridine-3-acetic acid 

Relevant articles and documents

Synthesis of [123I]N',N'-dimethyl-6-methyl-(4'-iodophenyl)imidazo[1,2-a]pyridine-3-acetamide for the study of peripheral benzodiazepine receptors using SPECT

The [123I] labelled imidazo[1,2-a]pyridine [123I]iodozolpidem 4 was found to exhibit preferential activity towards Peripheral rather than Central Benzodiazepine receptors in vivo and was synthesised for the potential study of the Peripheral Benzodiazepine Receptors (PBR) using SPECT. [123I]Iodozolpidem was prepared from the corresponding tributyl tin precursor by iododestannylation with Na[123I] in the presence of peracetic acid or chloramine-T. Purification by semipreparative C-18 RP HPLC gave the product in radiochemical yields of 60-85%. The product was obtained in > 97% chemical and radiochemical puritiy with a specific activity > 80 GBq/μmol.