27446-08-8

Basic information

• Product Name: 1,2,4-Benzotriazin-3(2H)-one, 1-oxide
• CAS NO: 27446-08-8
• Molecular Formula: C7H5N3O2
• Molecular Weight: 163.136
• Mol File: 27446-08-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1,2,4-Benzotriazin-3(2H)-one, 1-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2,4-Benzotriazin-3(2H)-one, 1-oxide(27446-08-8)
• EPA Substance Registry System: 1,2,4-Benzotriazin-3(2H)-one, 1-oxide(27446-08-8)

Safety Data

• Hazardous Substances Data: 27446-08-8(Hazardous Substances Data)

Upstream product

• 5424-06-6 3-amino-1,2,4-benzotriazine 1-oxide 

Downstream Products

• 67692-91-5 3-chloro-1,2,4-benzotriazine 1-oxide 
• 77475-32-2 ethyl 2-(benzo[e][1,2,4]triazin-3-yl)acetate 
• 91669-21-5 3-chlorobenzo[e][1,2,4]triazine 
• 96583-60-7 3-(4-nitrophenyl)-1,2,4-benzotriazine 1-oxide 
• 108954-09-2 toluene-4-sulfonic acid-[N'-(1-oxy-benzo[e][1,2,4]triazin-3-yl)-hydrazide] 
• 1016-90-6 7-nitro-1,2,4-benzotriazin-3-amine 1-oxide 
• 27314-97-2 3-amino-1,2,4-benzotriazine-1,4-dioxide 
• 5424-06-6 3-amino-1,2,4-benzotriazine 1-oxide 
• 83702-30-1 4-(2-Acetoxyethoxymethyl)-4H-benzo-1,2,4-triazin-3-one 1-Oxide 
• 83702-32-3 4-(2-Hydroxyethoxymethyl)-4H-benzo-1,2,4-triazin-3-one 1-Oxide 
• 83702-25-4 4-Benzyl-4H-benzo-1,2,4-triazin-3-one 1-Oxide 
• 54215-05-3 2-[(1-oxido-1,2,4-benzotriazin-3-yl)amino]ethanol 

Relevant articles and documents

Transferring oxygen isotopes to 1,2,4-benzotriazine 1-oxides forming the corresponding 1,4-dioxides by using the HOF·CH3CN complex

Heterocyclic benzotriazine N-oxides are an interesting class of experimental anticancer and antibacterial agents. Analogs with 18O incorporated into the N-oxide group may offer useful mechanistic tools. We describe the use of H218OF·CH3CN in a fast, readily executed and high-yielding preparation of 1,2,4-benzotriazine 1,4-dioxides containing an 18O-label at the 4-oxide position.