274914-47-5

Basic information

• Product Name: 3-methoxycarbonylmethyl-4-naphthalen-2-yl-1-(9-phenyl-9H-fluoren-9-yl)-2,5-dihydro-1H-pyrrole-2-carboxylic acid benzyl ester
• Synonyms: 3-methoxycarbonylmethyl-4-naphthalen-2-yl-1-(9-phenyl-9H-fluoren-9-yl)-2,5-dihydro-1H-pyrrole-2-carboxylic acid benzyl ester
• CAS NO: 274914-47-5
• Molecular Weight: 641.766
• Mol File: 274914-47-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-methoxycarbonylmethyl-4-naphthalen-2-yl-1-(9-phenyl-9H-fluoren-9-yl)-2,5-dihydro-1H-pyrrole-2-carboxylic acid benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-methoxycarbonylmethyl-4-naphthalen-2-yl-1-(9-phenyl-9H-fluoren-9-yl)-2,5-dihydro-1H-pyrrole-2-carboxylic acid benzyl ester(274914-47-5)
• EPA Substance Registry System: 3-methoxycarbonylmethyl-4-naphthalen-2-yl-1-(9-phenyl-9H-fluoren-9-yl)-2,5-dihydro-1H-pyrrole-2-carboxylic acid benzyl ester(274914-47-5)

Safety Data

• Hazardous Substances Data: 274914-47-5(Hazardous Substances Data)

Upstream product

• 32316-92-0 naphthalene-2-boronic acid 
• 163594-20-5 (2S)-benzyl-3-methoxycarbonylmethyl-Δ³-4-triflyloxy-N-(PhF)prolinate 

Downstream Products

• 274914-53-3 3-carboxymethyl-4-naphthalen-2-yl-1-(9-phenyl-9H-fluoren-9-yl)-2,5-dihydro-1H-pyrrole-2-carboxylic acid 

Relevant articles and documents

Synthesis and pharmacology of new enantiopure Δ3-4-arylkainoids

Seven Δ3-4-arylkainoids possessing various 4-position aromatic and heteroaromatic groups were synthesized and their apparent affinities were measured in order to explore the influences of 4-position electron density and stereochemistry on receptor affinity and specificity. Kainoids 1a-f were shown to be selective agonists at the NMDA receptor and the electron rich furanyl and thienyl analogues exhibited the highest affinities. Naphthylkainoid 1g proved to be a nonselective antagonist at the iGluRs. (C) 2000 Elsevier Science Ltd. All rights reserved.