2751-27-1

Basic information

• Product Name: 4-Iodobenzenesulfonohydrazide
• Synonyms: 4-Iodobenzenesulfonohydrazide
• CAS NO: 2751-27-1
• Molecular Formula: C₆H₇IN₂O₂S
• Molecular Weight: 298.10145
• Mol File: 2751-27-1.mol
• Article Data: 12

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• CAS DataBase Reference: 4-Iodobenzenesulfonohydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Iodobenzenesulfonohydrazide(2751-27-1)
• EPA Substance Registry System: 4-Iodobenzenesulfonohydrazide(2751-27-1)

Safety Data

• Hazardous Substances Data: 2751-27-1(Hazardous Substances Data)

Usage

General Description

4-Iodobenzenesulfonohydrazide is a chemical compound with the molecular formula C6H6IN2O2S. It is a white to off-white solid that is primarily used as a reagent in organic synthesis. 4-Iodobenzenesulfonohydrazide is commonly utilized in the preparation of various pharmaceuticals, agrochemicals, and other organic compounds. It is a versatile building block in the synthesis of heterocycles, especially in the preparation of sulfonamide and sulfonyl hydrazones. Additionally, 4-Iodobenzenesulfonohydrazide has been reported to possess antimicrobial and antifungal activity. It has also been investigated for its potential use as a corrosion inhibitor and as a reagent for the determination of various metals in analytical chemistry.

Upstream product

• 98-61-3 p-Iodobenzenesulfonyl chloride 

Downstream Products

• 108844-90-2 4-iodo-benzenesulfonic acid-(N'-ξ-D-glucopyranosyl-hydrazide) 
• 18559-20-1 D-erythro-Pentulose-<4-jod-benzolsulfonylhydrazon> 
• 1448709-49-6 3-((4-iodophenyl)thio)-1H-indole 
• 1554261-69-6 C₁₆H₁₇IOS 
• 3001-15-8 4,4'-diiodobiphenyl 
• 861083-81-0 (4-iodophenyl)(4-methoxyphenyl)thioether 
• 1591-31-7 4-iodo-biphenyl 
• 4241-66-1 4-Iodobenzenesulphonyl Fluoride 
• 6202-59-1 2-(4-iodophenyl)-1H-indole 
• 130188-82-8 2-[(4-iodophenyl)sulfonyl]-1-phenylethanone 
• 1338595-39-3 (4-iodophenyl)(naphthalen-2-yl)sulfane 
• 22950-14-7 4-((4-iodophenyl)sulfonyl)morpholine 
• 832744-33-9 1-bromo-4-(2-(4-iodophenyl)ethynyl)benzene 
• 64984-08-3 1-iodo-4-(methylsulfonyl)benzene 

Relevant articles and documents

Palladium-Catalyzed Direct C-H Arylation of 3-Butenoic Acid Derivatives

We report herein a direct method to synthesize 4-aryl-3-butenoic acid through a carboxylic-acid-directed oxidative Heck reaction. The various 4-aryl-3-butenoic acids are easily prepared in moderate to good yields. In view of the promising bioactivity of 4-phenyl-3-butenoic acid previously reported, its derivatives reported here may be bioactive.

The synthesis of sulfonated 4: H -3,1-benzoxazines via an electro-chemical radical cascade cyclization

A new route for the synthesis of sulfonated 4H-3,1-benzoxazines has been accomplished by electrochemical radical cascade cyclizations of styrenyl amides with sulfonylhydrazines. This process demonstrates a wide substrate scope with diverse functional group compatibility under metal- and external oxidant-free conditions at ambient temperature.

Copper-Catalyzed Radical Cascade Cyclization to Access 3-Sulfonated Indenones with the AIE Phenomenon

An efficient copper-catalyzed radical cascade cyclization strategy was developed, by which a wide variety of 3-sulfonyl substituted indenones were prepared in one pot via reaction of 2-alkynylbenzonitriles with sulfonyl hydrazides in the presence of TBHP and CuI under mild reaction conditions. Much more importantly, the 3-sulfonyl indenones, synthesized through our newly developed copper-catalyzed radical cascade cyclization strategy, were found to own typical aggregation-induced emission (AIE) properties, showing orange to red emission with large Stokes shift (more than 135 nm). In addition, such newly found AIEgens could be successfully used in live cell imaging, exhibiting excellent biocompatibility and application potential.