27537-72-0 Usage
Description
Estrone β-D-Glucuronide Triacetate Methyl Ester is a metabolite derived from 17β-Estradiol (E888000), which is a naturally occurring hormone in the body. It is characterized by its white solid appearance and is primarily used in the preparation of Estrone (E889050).
Uses
Used in Pharmaceutical Industry:
Estrone β-D-Glucuronide Triacetate Methyl Ester is used as an intermediate compound for the synthesis of Estrone (E889050), which has various applications in the pharmaceutical industry. It plays a crucial role in the development and production of medications related to hormone regulation and replacement therapies.
Used in Research and Development:
In the field of research and development, Estrone β-D-Glucuronide Triacetate Methyl Ester serves as an essential compound for studying the metabolic pathways and biological functions of 17β-Estradiol and Estrone. This knowledge can contribute to the understanding of hormonal imbalances and the development of targeted therapies for various conditions.
Used in Hormone Replacement Therapy:
Estrone β-D-Glucuronide Triacetate Methyl Ester is used as a precursor in the production of Estrone, which is an essential hormone for hormone replacement therapy. This therapy is particularly important for women experiencing menopause, as it helps alleviate symptoms and maintains overall health.
Used in Endocrinology:
In the field of endocrinology, Estrone β-D-Glucuronide Triacetate Methyl Ester is utilized for studying the role of Estrone in various physiological processes. This research can lead to a better understanding of hormonal regulation and the development of treatments for endocrine disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 27537-72-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,7,5,3 and 7 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 27537-72:
(7*2)+(6*7)+(5*5)+(4*3)+(3*7)+(2*7)+(1*2)=130
130 % 10 = 0
So 27537-72-0 is a valid CAS Registry Number.
27537-72-0Relevant articles and documents
Synthesis of β-glucuronides of estradiol, ethynylestradiol and estrone
Werschkun, Barbara,Gorziza, Karin,Thiem, Joachim
, p. 629 - 637 (2007/10/03)
Improved syntheses for the 3-β-D-glucuronides of the steroidal sex hormones 17β-estradiol, 17α-ethynylestradiol and estrone are reported employing boron trifluoride diethyl etherate catalysis with tetraacetylated glucuronic acid or the corresponding imidate.
