276252-75-6

Basic information

• Product Name: (R)-4-Amino-3-(4-chloro-phenyl)-1-((2S,6S)-2,6-dimethyl-morpholin-4-yl)-butan-1-one
• Synonyms: (R)-4-Amino-3-(4-chloro-phenyl)-1-((2S,6S)-2,6-dimethyl-morpholin-4-yl)-butan-1-one
• CAS NO: 276252-75-6
• Molecular Weight: 310.824
• Mol File: 276252-75-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-4-Amino-3-(4-chloro-phenyl)-1-((2S,6S)-2,6-dimethyl-morpholin-4-yl)-butan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-4-Amino-3-(4-chloro-phenyl)-1-((2S,6S)-2,6-dimethyl-morpholin-4-yl)-butan-1-one(276252-75-6)
• EPA Substance Registry System: (R)-4-Amino-3-(4-chloro-phenyl)-1-((2S,6S)-2,6-dimethyl-morpholin-4-yl)-butan-1-one(276252-75-6)

Safety Data

• Hazardous Substances Data: 276252-75-6(Hazardous Substances Data)

Upstream product

• 276252-73-4 (+/-)-trans-2,6-dimethylmorpholine 
• 125948-51-8 (S)-2-(((S)-1-hydroxypropan-2-yl)oxy)propan-1-ol 
• 276252-74-5 (R)-3-(4-Chloro-phenyl)-1-((2S,6S)-2,6-dimethyl-morpholin-4-yl)-4-nitro-butan-1-one 
• 276252-71-2 Methanesulfonic acid (S)-2-((S)-2-methanesulfonyloxy-1-methyl-ethoxy)-propyl ester 
• 276252-72-3 (2S,6S)-4-benzyl-2,6-dimethylmorpholine 
• 125948-52-9 S,S-dilactic acid diethyl ester 

Downstream Products

• 63701-55-3 (R)-(-)-baclofen hydrochloride 

Relevant articles and documents

Enantioselective synthesis of (R)-(-)-baclofen using Fischer-type carbene anions

The antispastic drug (R)-(-)-baclofen has been synthesized enantioselectively using a diastereoselective Michael addition reaction of the conjugate base of an enantiopure Fischer-type amino carbene to p-chloro-nitrostyrene. Copyright (C) 2000 Elsevier Science Ltd.