27643-19-2 Usage
Description
N-METHYL-2-PIPERIDINEMETHANAMINE, also known as Methyl[(piperidin-2-yl)methyl]amine, is an organic compound that serves as a crucial reagent in the chemical synthesis process. It is characterized by its amine functional group and a piperidine ring, which contribute to its unique chemical properties and reactivity.
Uses
Used in Pharmaceutical Industry:
N-METHYL-2-PIPERIDINEMETHANAMINE is used as a synthetic reagent for the production of various pharmaceutical compounds. Its ability to form 2-?azaindolizidines and other related derivatives makes it a valuable component in the development of novel drugs with potential therapeutic applications.
Used in Chemical Synthesis:
In the field of chemical synthesis, N-METHYL-2-PIPERIDINEMETHANAMINE is used as a building block for creating complex organic molecules. Its unique structure allows for the formation of diverse chemical entities, which can be further utilized in various applications, such as the development of new materials, dyes, and other specialty chemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 27643-19-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,7,6,4 and 3 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 27643-19:
(7*2)+(6*7)+(5*6)+(4*4)+(3*3)+(2*1)+(1*9)=122
122 % 10 = 2
So 27643-19-2 is a valid CAS Registry Number.
27643-19-2Relevant articles and documents
Compounds with Bridgehead Nitrogen 52 -NMR Spectra and Stereochemistry of the 2-Alkylperhydroimidazolopyridines
Banting, Lee,Crabb, Trevor A.
, p. 696 - 706 (2007/10/02)
In contrast to perhydro-oxazolopyridine and perhydrothiazolopyridine, which adopt equilibria in CDCl3 solution at room temperature containing ca 70percent trans-fused conformers in equilibria with O- or S-inside cis-fused conformers, 2-alkylperhydroimidazolopyridines are found to adopt equilibria containing >98percent trans-fused conformers.Comparison of NMR parameters of 2-methylperhydroimidazolopyridine with those of the two isomers of 1,2-dimethylperhydroimidazolopyridine indicates an equilibrium for the former compound between the two trans-fused conformers, with ca 83percent of that conformation containing a transarrangement of nitrogen lone pairs of electrons.These observations are explained in terms of the generalized anomeric effect.KEY WORDS Perhydroimidazolopyridine Conformational equilibria 1H and 13C NMR
