27644-80-0

Basic information

• Product Name: 2-(3-chloro-phenyl)-4,4-dimethyl-oxazolidine
• CAS NO: 27644-80-0
• Molecular Weight: 211.691
• Mol File: 27644-80-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(3-chloro-phenyl)-4,4-dimethyl-oxazolidine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3-chloro-phenyl)-4,4-dimethyl-oxazolidine(27644-80-0)
• EPA Substance Registry System: 2-(3-chloro-phenyl)-4,4-dimethyl-oxazolidine(27644-80-0)

Safety Data

• Hazardous Substances Data: 27644-80-0(Hazardous Substances Data)

Upstream product

• 124-68-5 2-Amino-2-methyl-1-propanol 
• 587-04-2 m-Chlorobenzaldehyde 

Downstream Products

• 80762-49-8 2-(m-chlorophenyl)-4,4-dimethyl-4,5-dihydrooxazole 

Relevant articles and documents

Directed functionalization of halophenyl-2-oxazolines with TMPMgCl?LiCl

A variety of difunctionalized aryl-2-oxazolines were prepared from the reaction of halophenyl-2-oxazolines and TMPMgCl?LiCl to give an organomagnesium reagent, which was then treated with various electrophiles. The metalation step takes place under mild conditions, and this process al-lows for the isolation of the desired products in good yields. No isomeric or other benzyne-derived products were detected. The influence of the halogen substituents on the acidity of the aromatic hydrogen atoms was evaluated by using density functional theory (DFT) calculations.