27653-10-7

Basic information

• Product Name: 2H-1,2,3-Triazole, 2,4,5-triphenyl-
• CAS NO: 27653-10-7
• Molecular Formula: C20H15N3
• Molecular Weight: 297.359
• Mol File: 27653-10-7.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: 2H-1,2,3-Triazole, 2,4,5-triphenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-1,2,3-Triazole, 2,4,5-triphenyl-(27653-10-7)
• EPA Substance Registry System: 2H-1,2,3-Triazole, 2,4,5-triphenyl-(27653-10-7)

Safety Data

• Hazardous Substances Data: 27653-10-7(Hazardous Substances Data)

Upstream product

• 6630-86-0 benzil phenylhydrazone 
• 29094-98-2 triphenyl-2H-[1,2,3,6]thiatriazine 
• 64-19-7 acetic acid 
• 1695-80-3 benzil bisphenylhydrazone 
• 119-53-9 2-hydroxy-2-phenylacetophenone 
• 100-63-0 phenylhydrazine 
• 451-40-1 phenyl benzyl ketone 
• 952-06-7 deoxybenzoin oxime 
• 369-57-3 benzenediazonium tetrafluoroborate 
• 16483-98-0 2,3-diphenyl-2H-azirine 
• 591-50-4 iodobenzene 
• 501-65-5 diphenyl acetylene 
• 120106-62-9 4,5-diphenyl-2H-1,2,3-triazole 
• 16717-64-9 1-azidostyrene 

Downstream Products

• 180779-85-5 1,3,3a-Triphenyl-3a,6-dihydro-1H-pyrrolo[1,2-c][1,2,3]triazole-4,5-dicarboxylic acid dimethyl ester 
• 100-47-0 benzonitrile 
• 130720-56-8 4,5-diphenyl-1-phenylamino-1H-imidazole 
• 130720-50-2 2,5,6-Triphenyl-2,3-dihydro-[1,2,4]triazine 

Relevant articles and documents

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Catalyst-Free Regioselective N2 Arylation of 1,2,3-Triazoles Using Diaryl Iodonium Salts

The widespread application of 1,2,3-triazoles in pharmaceuticals has resulted in substantial interest toward developing efficient postmodification methods. Whereas there are many postmodification methods available to obtain N1-substituted 1,2,3-triazoles, developing a selective and convenient protocol to synthesize N2-aryl-1,2,3-triazoles has been challenging. We report a catalyst-free and regioselective method to access N2-aryl-1,2,3-triazoles in good to excellent yields (66-97%). This scalable postmodification protocol is effective for a wide range of substrates.

Regiospecific Synthesis of N 2-Aryl 1,2,3-Triazoles from 2,5-Disubstituted Tetrazoles via Photochemically Generated Nitrile Imine Intermediates

The synthesis of N2-aryl 1,2,3-triazoles from 2,5-disubstituted tetrazoles was achieved under photochemical conditions. This simple and mild one-step reaction provides regiospecific access to 2,4,5-substituted 1,2,3-triazoles via a nitrile imine intermediate. Syntheses of alkyl and heterocylic derivatives were also investigated.