276702-20-6

Basic information

• Product Name: 3-aMino-6-chloro-2-hydroxybenzenesulfonaMide
• Synonyms: 3-aMino-6-chloro-2-hydroxybenzenesulfonaMide
• CAS NO: 276702-20-6
• Molecular Formula: C₆H₇ClN₂O₃S
• Molecular Weight: 222.64938
• Mol File: 276702-20-6.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-aMino-6-chloro-2-hydroxybenzenesulfonaMide(CAS DataBase Reference)
• NIST Chemistry Reference: 3-aMino-6-chloro-2-hydroxybenzenesulfonaMide(276702-20-6)
• EPA Substance Registry System: 3-aMino-6-chloro-2-hydroxybenzenesulfonaMide(276702-20-6)

Safety Data

• Hazardous Substances Data: 276702-20-6(Hazardous Substances Data)

Upstream product

• 761448-08-2 2-tert-butyl-6-chloro-benzooxazole-7-sulfonic acid amide 
• 276702-19-3 2-hydroxy-3-nitro-6-chlorobenzenesulfonamide 

Downstream Products

• 360789-17-9 N-(3-aminosulfonyl-4-chloro-2-hydroxyphenyl)-N'-phenethylurea 
• 361392-30-5 N-(3-aminosulfonyl-4-chloro-2-hydroxyphenyl)-N'-(3,5-dimethylisoxazol4-yl)urea 
• 361378-87-2 N-(3-aminosulfonyl4-chloro-2-hydroxyphenyl)-N'-(2-methyl)benzylurea 
• 361391-74-4 6-Chloro-2-hydroxy-3-(3-piperidin-4-yl-ureido)-benzenesulfonamide 
• 360789-14-6 N-(3-aminosulfonyl-4-chloro-2-hydroxyphenyl)-N'-ethylurea 
• 361391-69-7 N-(3-aminosulfonyl-4-chloro-2-hydroxyphenyl)-N'-(1-adamantyl)urea 
• 361378-86-1 N-(3-aminosulfonyl4-chloro-2-hydroxyphenyl)-N'-benzylurea 
• 360789-12-4 N-allyl-N'-(3-aminosulfonyl-4-chloro-2-hydroxyphenyl)urea 
• 360789-13-5 N-(3-aminosulfonyl-4-chloro-2-hydroxyphenyl)-N'-isopropylurea 
• 360789-15-7 N-(3-aminosulfonyl-4-chloro-2-hydroxyphenyl)-N'-propylurea 
• 360789-20-4 N-(3-aminosulfonyl-4-chloro-2-hydroxyphenyl)-N'-2-methylpentanyl urea 
• 1026699-05-7 N-[4-chloro-2-hydroxy-3-sulfamylphenyl]-N'-(3-tetrahydrofuryl)urea 
• 361391-78-8 N-(3-aminosulfonyl-4-chloro-2-hydroxyphenyl)-N'-cyclobutyl urea 
• 360789-19-1 6-Chloro-3-[3-(1-ethyl-propyl)-ureido]-2-hydroxy-benzenesulfonamide 

Relevant articles and documents

Discovery of potent and orally bioavailable N,N′-diarylurea antagonists for the CXCR2 chemokine receptor

A series of 3-substituted N,N′-diarylureas was prepared and CXCR2 receptor affinities as well as pharmacokinetic properties were examined. A series of 3-substituted N,N′-diarylureas was prepared and the structure-activity relationship relative to CXCR2 re

3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands

There are disclosed compounds of the formula or a pharmaceutically acceptable salt or solvate thereof which are useful for the treatment of chemokine-mediated diseases such as acute and chronic inflammatory disorders and cancer.

Il-8 receptor antagonists

This invention relates to novel compounds of Formula (I) to (VII), and compositions thereof, useful in the treatment of disease states mediated by the chemokine, Interleukin-8 (IL-8).