27686-50-6 Usage
Description
TRT-CYS(TRT)-OH, also known as Trt-Cys(Trt)-OH, is a trityl-protected derivative of cysteine, a naturally occurring amino acid. It is characterized by its protective trityl group, which plays a crucial role in its applications. TRT-CYS(TRT)-OH is known for its ability to inhibit human mitotic kinesin, a motor protein involved in cell division, making it a valuable compound in the field of biomedical research.
Uses
Used in Biomedical Applications:
TRT-CYS(TRT)-OH is used as a building block for the synthesis of protein dendrimers, which are highly branched, nanoscale structures with potential applications in various fields, including drug delivery, diagnostics, and therapeutics. The trityl-protected cysteine derivative contributes to the structural integrity and functionality of these dendrimers, enhancing their performance in biomedical applications.
Used in Pharmaceutical Research:
As an inhibitor of human mitotic kinesin, TRT-CYS(TRT)-OH is employed in the development of drugs targeting cell division and proliferation. This makes it a valuable tool in the research and development of therapeutics for various diseases, including cancer, where the inhibition of cell division is a critical aspect of treatment.
Used in Chemical Synthesis:
TRT-CYS(TRT)-OH is also used as a key component in the synthesis of various chemical compounds, particularly those involving the modification or protection of cysteine residues. Its trityl group provides a stable and easily removable protecting group, facilitating the synthesis of complex molecules with specific properties and functions.
Check Digit Verification of cas no
The CAS Registry Mumber 27686-50-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,7,6,8 and 6 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 27686-50:
(7*2)+(6*7)+(5*6)+(4*8)+(3*6)+(2*5)+(1*0)=146
146 % 10 = 6
So 27686-50-6 is a valid CAS Registry Number.
27686-50-6Relevant articles and documents
Preparation of N-Tritylamino Acids from N-Trimethylsilylamino Acid Trimethylsilyl Esters
Mamos, Petros,Sanida, Chariklia,Barlos, Kleomenis
, p. 1083 - 1084 (2007/10/02)
Persilylated amino acids are used to prepare Nα-tritylamino acids 2,4, and 6 in high yields by cleavage of the Si-N bond with trityl chloride in chloroform under reflux.The side chains of Lys, Orn and Cys are simultaneously tritylated while sil
Structural modification of S-trityl-L-cysteine. Preparation of some S-(substituted trityl)-L-cysteines and dipeptides of S-trityl-L-cysteine.
Zee-Cheng,Cheng
, p. 13 - 16 (2007/10/06)
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