27689-95-8 Usage
General Description
Trimethyl 4-hydroxyorthobenzoate is a chemical compound commonly known as methylparaben. It is a member of the paraben family, which are widely used as preservatives in pharmaceuticals, personal care products, and food. Methylparaben is effective in preventing the growth of bacteria and fungi, extending the shelf life of products. It is also used as a fragrance ingredient and as a UV filter in sunscreen products. However, there is some controversy surrounding the safety of parabens, with concerns about their potential to disrupt hormone function and their possible role in the development of certain health conditions. As a result, there has been a movement towards using alternative preservatives in products.
Check Digit Verification of cas no
The CAS Registry Mumber 27689-95-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,7,6,8 and 9 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 27689-95:
(7*2)+(6*7)+(5*6)+(4*8)+(3*9)+(2*9)+(1*5)=168
168 % 10 = 8
So 27689-95-8 is a valid CAS Registry Number.
InChI:InChI=1/C10H14O4/c1-12-10(13-2,14-3)8-4-6-9(11)7-5-8/h4-7,11H,1-3H3
27689-95-8Relevant articles and documents
Synthesis of esters by selective methanolysis of the trifluoromethyl group
Ramig, Keith,Englander, Miriam,Kallashi, Florida,Livchits, Lilia,Zhou, Jessica
, p. 7731 - 7734 (2002)
The trifluoromethyl group of certain compounds containing one or two trifluoromethyl groups can be converted to the carbomethoxy group by treatment with sodium methoxide followed by aqueous acidic work-up. α-Trifluoromethyl esters can be obtained by selective methanolysis of the 1,1,1,3,3,3-hexafluoroisopropyl group in some cases. The structural requirements for the transformation are delineated, and a mechanistic study confirms the proposed mechanism, a dehydrofluorination-addition-elimination process.
