277297-33-3

Basic information

• Product Name: 2-((S)-1-Allyl-pentyl)-5-((S)-2-methyl-pent-4-enyl)-benzene-1,3-diol
• Synonyms: 2-((S)-1-Allyl-pentyl)-5-((S)-2-methyl-pent-4-enyl)-benzene-1,3-diol
• CAS NO: 277297-33-3
• Molecular Weight: 302.457
• Mol File: 277297-33-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-((S)-1-Allyl-pentyl)-5-((S)-2-methyl-pent-4-enyl)-benzene-1,3-diol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-((S)-1-Allyl-pentyl)-5-((S)-2-methyl-pent-4-enyl)-benzene-1,3-diol(277297-33-3)
• EPA Substance Registry System: 2-((S)-1-Allyl-pentyl)-5-((S)-2-methyl-pent-4-enyl)-benzene-1,3-diol(277297-33-3)

Safety Data

• Hazardous Substances Data: 277297-33-3(Hazardous Substances Data)

Upstream product

• 246144-90-1 (4R,5S)-3-((S)-2-allylhexanoyl)-4-methyl-5-phenyloxazolidin-2-one 
• 246144-98-9 (S)-3-Allyl-1,1-dibromo-heptan-2-one 
• 246144-83-2 2-butyl-pent-4-enoic acid ethyl ester 
• 353291-30-2 (S)-2-allylhexanoic acid 
• 131636-15-2 (4R,5S)-3-hexanoyl-4-methyl-5-phenyloxazolidin-2-one 
• 277297-32-2 3-((S)-2-Methyl-pent-4-enyl)-cyclobut-2-enone 
• 277297-31-1 (S)-5-Iodo-4-methyl-pent-1-ene 
• 5673-98-3 (S)-(-)-2-methyl-4-penten-1-ol 
• 246144-80-9 (3-butyl-hex-5-en-1-ynyloxy)-triisopropyl-silane 

Downstream Products

• 277297-34-4 2-((S)-1-Allyl-pentyl)-1,3-dimethoxy-5-((S)-2-methyl-pent-4-enyl)-benzene 

Relevant articles and documents

Total synthesis of ( - )-cylindrocyclophanes A and F exploiting the reversible nature of the olefin cross metathesis reaction

Efficient total syntheses of the C2-symmetric ( - )-cylindrocyclophanes A and F (1a and 1f) have been achieved. The initial strategy featured the use of a common advanced intermediate to assemble in stepwise fashion the required macrocycle of 1f, exploiting in turn a Myers reductive coupling followed by ring-closing metathesis. In a second-generation strategy, a remarkable cross olefin metathesis dimerization cascade was discovered and exploited to assemble the requisite [7,7]-paracyclophane macrocycles of both 1a and 1f from dienyl monomers. The successful syntheses also featured the effective use of the Danheiser annulation to construct substrates for both the Myers reductive coupling and the metathesis dimerizations strategies. Finally, the Kowalski two-step chain homologation of esters to siloxyalkynes proved superior over the original one-step protocol.