277331-17-6

Basic information

• Product Name: Benzenemethanol, 2-chloro-3-hydroxy-
• Synonyms: Benzenemethanol, 2-chloro-3-hydroxy-;2-chloro-3-(hydroxymethyl)phenol
• CAS NO: 277331-17-6
• Molecular Formula: C₇H₇ClO₂
• Molecular Weight: 158.58
• Mol File: 277331-17-6.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Benzenemethanol, 2-chloro-3-hydroxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanol, 2-chloro-3-hydroxy-(277331-17-6)
• EPA Substance Registry System: Benzenemethanol, 2-chloro-3-hydroxy-(277331-17-6)

Safety Data

• Hazardous Substances Data: 277331-17-6(Hazardous Substances Data)

Usage

General Description

"Benzenemethanol, 2-chloro-3-hydroxy-" is a chemical compound with the molecular formula C7H7ClO2. It is a derivative of benzenemethanol, containing a chlorine atom and a hydroxyl group at different positions on the benzene ring. Benzenemethanol, 2-chloro-3-hydroxy- is used in the synthesis of pharmaceuticals and other organic compounds. It has also been studied for its potential pharmacological properties and biological activities. However, it is important to handle this chemical with caution, as it may have harmful effects on human health and the environment if not properly managed.

Upstream product

• 56962-10-8 2-chloro-3-hydroxybenzaldehyde 
• 100-83-4 meta-hydroxybenzaldehyde 
• 51786-10-8 2-Chloro-3-hydroxy benzoic acid 

Downstream Products

• 52516-43-5 2-chloro-3-methoxybenzyl alcohol 
• 277331-18-7 (2-chloro-3-hydroxymethylphenoxy)acetic acid methyl ester 
• 1255206-92-8 4-bromo-2-chloro-3-(hydroxymethyl)phenol 
• 1256560-84-5 3-(bromomethyl)-2-chlorophenol 

Relevant articles and documents

FACTOR XI ACTIVATION INHIBITORS

The present invention provides a compound of Formula (I) and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing thromboses, embolisms, hypercoagulability or fibrotic changes. The compounds are selective Factor XI activation inhibitors.

INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL

The present invention provides compounds of Formula I and the pharmaceutically acceptable salts thereof, which are inhibitors of the ROMK (Kirl.1) channel. The compounds may be used as diuretic and/or natriuretic agents and for the therapy and prophylaxis of medical conditions including cardiovascular diseases such as hypertension, heart failure and conditions associated with excessive salt and water retention.

INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL

The present invention provides compounds of Formula (I) and the pharmaceutically acceptable salts thereof, which are inhibitors of the ROMK (Kir1.1) channel. The compounds act as diuretics and natriuretics and are valuable pharmaceutically active compounds for the therapy and prophylaxis of medical conditions including cardiovascular diseases such as hypertension and conditions resulting from excessive salt and water retention.