2774-84-7 Usage
Description
10-Undecyn-1-ol is an acetylenic alcohol characterized by its antifungal properties and versatile applications in various industries, including pharmaceuticals and synthetic chemistry. It is known for its ability to participate in esterification reactions and act as a reagent and intermediate in organic synthesis processes.
Uses
Used in Pharmaceutical Industry:
10-Undecyn-1-ol is used as an antifungal agent for its ability to combat fungal infections. Its antifungal activity makes it a valuable component in the development of medications and treatments targeting various fungal pathogens.
Used in Synthetic Chemistry:
10-Undecyn-1-ol is used as a reagent in the preparation of 11-bromo-undec-1-yne by reacting with carbon tetrabromide and triphenylphosphine. This reaction showcases its utility in creating complex organic compounds for further research and development.
Used in Esterification Processes:
10-Undecyn-1-ol is used as a reactant in the esterification of pentanoic and stearic acids in the presence of various lipases. This application highlights its role in the production of esters, which have a wide range of uses in the chemical and pharmaceutical industries.
Used as an Intermediate in Organic Synthesis:
10-Undecyn-1-ol serves as an intermediate in synthetic chemistry, contributing to the synthesis of more complex molecules and compounds. Its versatility in participating in various chemical reactions makes it a valuable component in the development of new materials and products.
Synthesis Reference(s)
The Journal of Organic Chemistry, 60, p. 7884, 1995 DOI: 10.1021/jo00129a031
Check Digit Verification of cas no
The CAS Registry Mumber 2774-84-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,7,7 and 4 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 2774-84:
(6*2)+(5*7)+(4*7)+(3*4)+(2*8)+(1*4)=107
107 % 10 = 7
So 2774-84-7 is a valid CAS Registry Number.
InChI:InChI=1/C11H20O/c1-2-3-4-5-6-7-8-9-10-11-12/h1,12H,3-11H2
2774-84-7Relevant articles and documents
Lindhoudt,J.C. et al.
, p. 2565 - 2568 (1976)
Stereoselective synthesis of C3–C17 and C18–C34 subunits of bullatanocin utilizing α-chloro sulfide intermediates
Chowhan, L. Raju,Raghavan, Sadagopan
, (2019)
A convergent synthesis of bullatanocin is envisaged by the union of C18–C34, C3–C17 and the butenolide subunits. The synthesis of the C3–C17 and C18–C34 subunits is disclosed that takes advantage of the chirality of tartaric acid for 1,2-asymmetric induct
Stereoselective Synthesis of Perfluoroalkylated (E,E)-Dienes from Perfluoroalkylated Alkynes. The Synthesis of Fluorinated Analogs of Lepidoptera Pheromones
Wang, Zhong,Lu, Xiyan
, p. 11765 - 11774 (1995)
Pd(dba)2 -HOAc catalyzed the isomerization of 1-perfluoroalkyl-1-alkynes to give 1-perfluoroalkyl-(1E,3E)-dienes in good yield and stereoselectivity; the fluorinated analogs of Lepidoptera species sex pheromone attractants were synthesized applying this method.
IMMUNOTHERAPEUTIC AGENT
-
, (2018/07/29)
Compounds for use in the treatment of sepsis and/or the prevention or treatment of post-sepsis syndrome.
Enantioselective Rhodium-Catalyzed Atom-Economical Macrolactonization
Ganss, Stephanie,Breit, Bernhard
, p. 9738 - 9742 (2016/08/10)
A highly attractive route toward macrolactones, which form the cyclic scaffold of a multitude of diverse natural compounds, is described. Although many chemical approaches to this structural motif have been explored, an asymmetric variant of the cyclization is unprecedented. Herein we present an enantioselective macrolactonization through an intramolecular atom-economical rhodium-catalyzed coupling of ω-allenyl-substituted carboxylic acids. The use of a modified diop ligand, chiral DTBM-diop, led to high enantioselectivity (up to 93 % ee). The reaction tolerated a large variety of functionalities, including α,β-unsaturated carboxylic acids and depsipeptides, and provided the desired macrocycles with very high enantio- and diastereoselectivity.
