27751-82-2Relevant articles and documents
Hydrazone-based derivative, intermediate, preparation method, pharmaceutical composition and applications thereof
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, (2019/10/01)
The present invention discloses a hydrazone-based derivative (I), an intermediate, a preparation method, a pharmaceutical composition and applications thereof, wherein the hydrazone-based compound hasgood inhibitory effect on the ubiquitination activity of cIAP1 protein, can promote the degradation of oncogenic protein c-MYC at a cellular level so as to inhibit the growth of tumor cells, and hasbroad drug development prospects.