2776-93-4

Basic information

• Product Name: 2-ACETAMIDO-1-BETA-[L-ASPARTAMIDO]-1,2-DIDEOXY-D-GLUCOSE
• Synonyms: n-acetylglucosaminylasparagine;2-ACETAMIDO-1-BETA-[L-ASPARTAMIDO]-1,2-DIDEOXY-D-GLUCOSE;2-ACETAMIDO-1-N-(BETA-L-ASPARTYL)-2-DEOXY-BETA-D-GLUCOPYRANOSYLAMINE;BETA-D-GLCNAC-1->N-ASN;2-acetamido-1-N(B-L-aspartyl)-2 deoxy*B-D-glucopy;2-ACETAMIDO-1-N(B-L-ASPARTYL)-2 DEOXYB-D -GLUCOPYRA;n-asn;β-d-glcnac-1→n-asn
• CAS NO: 2776-93-4
• Molecular Formula: C₁₂H₂₁N₃O₈
• Molecular Weight: 335.31
• Mol File: 2776-93-4.mol
• Article Data: 3

Chemical Properties

• Melting Point: 264-266 °C (decomp)(Solv: water (7732-18-5); ethanol (64-17-5))
• Boiling Point: 818.5°Cat760mmHg
• Flash Point: 448.8°C
• Appearance: /
• Density: 1.53g/cm³
• Vapor Pressure: 4.86E-31mmHg at 25°C
• Refractive Index: 1.6
• Storage Temp.: −20°C
• Solubility: DMSO (Slightly), Water (Slightly)
• PKA: 2.43±0.10(Predicted)
• Stability: Hygroscopic
• CAS DataBase Reference: 2-ACETAMIDO-1-BETA-[L-ASPARTAMIDO]-1,2-DIDEOXY-D-GLUCOSE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-ACETAMIDO-1-BETA-[L-ASPARTAMIDO]-1,2-DIDEOXY-D-GLUCOSE(2776-93-4)
• EPA Substance Registry System: 2-ACETAMIDO-1-BETA-[L-ASPARTAMIDO]-1,2-DIDEOXY-D-GLUCOSE(2776-93-4)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 2776-93-4(Hazardous Substances Data)

Usage

Description

2-ACETAMIDO-1-BETA-[L-ASPARTAMIDO]-1,2-DIDEOXY-D-GLUCOSE, also known as 2-Acetamido-1-N-(β-L-aspartyl)-2-deoxy-β-D-glucopyranosylamine, is an N4-glycosyl-L-asparagine with a beta-N-acetyl-D-glucosaminyl as the glycosyl component. It is a complex sugar molecule that plays a significant role in various biological processes and has potential applications in the medical field.

Uses

Used in Pharmaceutical Industry:
2-ACETAMIDO-1-BETA-[L-ASPARTAMIDO]-1,2-DIDEOXY-D-GLUCOSE is used as a diagnostic and therapeutic agent for renal disease. Its unique structure allows it to interact with specific biological targets, making it a valuable tool in the development of treatments for kidney-related conditions.
Used in Diagnostic Applications:
In the field of diagnostics, 2-ACETAMIDO-1-BETA-[L-ASPARTAMIDO]-1,2-DIDEOXY-D-GLUCOSE can be employed as a biomarker for the detection and monitoring of renal disease. Its presence in biological samples can indicate the presence or severity of kidney dysfunction, aiding in the early diagnosis and treatment of the condition.
Used in Research and Development:
Due to its unique structure and potential interactions with biological systems, 2-ACETAMIDO-1-BETA-[L-ASPARTAMIDO]-1,2-DIDEOXY-D-GLUCOSE can be used in research and development for the discovery of new therapeutic targets and the development of novel drugs for renal disease treatment.

InChI:InChI=1/C12H21N3O8/c1-4(17)14-8-10(20)9(19)6(3-16)23-11(8)15-7(18)2-5(13)12(21)22/h5-6,8-11,16,19-20H,2-3,13H2,1H3,(H,14,17)(H,15,18)(H,21,22)/t5-,6+,8+,9+,10+,11+/m0/s1

Upstream product

• 16405-05-3 2-acetamido-1-N-(1-benzyloxy-N-benzyloxycarbonyl-4-L-aspartyl)-2-deoxy-β-D-glucopyranosylamine 
• 4229-38-3 2-acetamido-2-deoxy-β-D-glucopyranosylamine 
• 7512-17-6 N-Acetyl-D-glucosamine 
• 4515-24-6 2-acetamido-2-deoxy-3,4,6-tri-O-acetyl-β-D-glucopyranosylamine 
• 4515-27-9 2-acetamido-3,4,6-tri-O-acetyl-1-N-[1-benzyl-N-(benzyloxy)carbonyl-L-aspart-4-oyl]-2-deoxy-β-D-glucopyranosylamine 

Downstream Products

• 90-76-6 2-deoxy-2-amino glucose 
• 56-84-8 L-Aspartic acid 
• 13010-39-4 aspartic acid β-hydrazide 
• 7512-17-6 N-Acetyl-D-glucosamine 
• 97055-07-7 1-(2-acetamido-2-deoxy-β-D-glucopyranosyl)-2-acetylhydrazine 

Relevant articles and documents

Enzymic synthesis of the sialylglycopeptide, α-D-NeupAc-(2->6)-β-D-Galp-(1->4)-β-D-GlcpNAc-(1->4N)-L-Asn

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The synthesis of 2-acetamido-1-N-(4-L-aspartyl)-2-deoxy-beta-D-galactopyranosylamine.

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