27770-80-5

Basic information

• Product Name: 4H-1-Benzopyran-4-one, 2,3-dihydro-2-(4-methoxyphenyl)-6-methyl-, (S)-
• CAS NO: 27770-80-5
• Molecular Formula: C17H16O3
• Molecular Weight: 268.312
• Mol File: 27770-80-5.mol
• Article Data: 14

Chemical Properties

• CAS DataBase Reference: 4H-1-Benzopyran-4-one, 2,3-dihydro-2-(4-methoxyphenyl)-6-methyl-, (S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 4H-1-Benzopyran-4-one, 2,3-dihydro-2-(4-methoxyphenyl)-6-methyl-, (S)-(27770-80-5)
• EPA Substance Registry System: 4H-1-Benzopyran-4-one, 2,3-dihydro-2-(4-methoxyphenyl)-6-methyl-, (S)-(27770-80-5)

Safety Data

• Hazardous Substances Data: 27770-80-5(Hazardous Substances Data)

Upstream product

• 135085-54-0 Acetic acid 2-[(E)-1-[(Z)-hydroxyimino]-3-(4-methoxy-phenyl)-allyl]-4-methyl-phenyl ester 
• 1450-72-2 5-methyl-2-hydroxyacetophenone 
• 123-11-5 4-methoxy-benzaldehyde 
• 16635-13-5 2'-hydroxy-4-methoxy-5'-methylchalcone 
• 1032-84-4 (E)-1-(2-hydroxy-5-methylphenyl)-3-(4-methoxyphenyl)prop-2-en-1-one 
• 64-19-7 acetic acid 
• 14221-83-1 (+/-)-3t-bromo-2r-(4-methoxy-phenyl)-6-methyl-chroman-4-one 
• 64-17-5 ethanol 
• 105166-57-2 2-Hydroxy-benzoic acid [2-(4-methoxy-phenyl)-6-methyl-chroman-(4E)-ylidene]-hydrazide 
• 22129-40-4 2'-hydroxy-4-methoxy-5'-methylchalcone dibromide 
• 61854-51-1 6-methyl-4'-methoxyflavanone hydrazone 
• 546-67-8 lead(IV) tetraacetate 
• 65612-70-6 4'-methoxy-6-methylflavanone oxime 

Downstream Products

• 29976-88-3 3-(2-hydroxy-5-methylphenyl)-5-(4-methoxyphenyl)-Δ²-isoxazoline 
• 29976-77-0 6-methyl-4'-methoxyflavone 
• 1032-84-4 (E)-1-(2-hydroxy-5-methylphenyl)-3-(4-methoxyphenyl)prop-2-en-1-one 
• 130252-75-4 3-(4-methoxyphenyl)-6-methyl-4H-chromen-4-one 
• 132314-56-8 2-(4-Methoxy-phenyl)-6-methyl-8-nitro-chroman-4-one 
• 81976-55-8 2,3-dihydro-2-(4-methoxyphenyl)-4H-6-methyl-benzopyran-4-one oxime 
• 30036-28-3 3-(2-acetoxy-5-methyl-phenyl)-5-(4-methoxyphenyl)-Δ²-isoxazoline 
• 81976-59-2 2,3-dihydro-2-(4-methoxyphenyl)-4H-6-methyl-benzopyran-4-one oxime acetate 
• 1393598-21-4 5-(4-methoxyphenyl)-9-methyl-2-piperidino-5H-chromeno[3,4-c]pyridine-1-carbonitrile 
• 1393598-14-5 4-chloro-2-(4-methoxyphenyl)-6-methyl-2H-chromene-3-carbaldehyde 
• 1266399-39-6 4-(4-methoxyphenyl)-8-methyl-4H-benzopyran[4,3-d][1,2,3]selenadiazole 
• 1266399-50-1 C₁₈H₁₉N₃O₃ 

Relevant articles and documents

Mild and efficient one-pot synthesis of diverse flavanone derivatives via an organocatalyzed Mannich-type reaction

A facile ethylenediamine diacetate (EDDA)-catalyzed one-pot synthesis of biologically interesting flavanone derivatives from 2-hydroxyacetophenones, aromatic aldehydes, and aniline via a Mannich-type reaction is described. This synthetic method provides a rapid access to biologically interesting flavanone derivatives. To demonstrate this method, several biologically interesting natural products bearing a flavanone moiety were synthesized as racemates.

Synthesis and cytotoxic activity of 4-aryl-4H-chromeno[4,3-d] [1,2,3] selenadiazoles

Fourteen 4-Aryl-4H-chromeno[4,3-d][1,2,3] selenadiazole derivatives were synthesized by the reaction of fla-vonone-4-semicarbazones with SeO2. The structures of the target compounds 1a-n were elucidated by 1H NMR, IR spectra, ESI-MS and elemental analyses. The preliminary cytotoxic activities of 1a-n against K562, KB, A549, SMC-7721 and SGC-7901 cell lines were evaluated by MTT method, indicating that most compounds displayed moderate to good antiproliferative activities against K562 and KB cell lines. Compounds 1m and 1n, the most potent ones, were promising template for development of novel potent antitumor agents.

Synthetic analogs of natural flavolignans. XV. Isomerization of 2′-hydroxychalcones into flavanones using triethylamine

A simple and effective method for preparing synthetic analogs of natural flavanones via isomerization of 2′-hydroxychalcones with triethylamine was proposed.