277751-71-0

Basic information

• Product Name: C₄₇H₈₈N₁₂O₁₉
• Synonyms: C₄₇H₈₈N₁₂O₁₉
• CAS NO: 277751-71-0
• Molecular Weight: 1125.28
• Mol File: 277751-71-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₄₇H₈₈N₁₂O₁₉(CAS DataBase Reference)
• NIST Chemistry Reference: C₄₇H₈₈N₁₂O₁₉(277751-71-0)
• EPA Substance Registry System: C₄₇H₈₈N₁₂O₁₉(277751-71-0)

Safety Data

• Hazardous Substances Data: 277751-71-0(Hazardous Substances Data)

Upstream product

• 119-04-0 neomycin B 

Downstream Products

• 277751-72-1 C₅₉H₁₀₆N₁₈O₁₉ 
• 277751-73-2 C₅₃H₁₀₀N₂₄O₁₉ 

Relevant articles and documents

Anti-(retro)viral conjugates of saccharides and acetamidino or guanidino compounds

Conjugates of a saccharide and an acetamidino- or guanidino-compound, of the formula: wherein A is CH3or NH2; X is a linear or branched C1-C8alkyl chain optionally containing hydroxy, amino and/or oxo groups; n is an integer from 1 to 6, and Sac is the residue of a mono-or oligo-saccharide, provided that when A is NH2and X is -(CH2)3—CH(NH2)—C(=O)-, the monosaccharide residue is not substituted at the position 1, and n is an integer from 2 to 6 when Sac is the residue of an oligosaccharide, are useful as antiviral, particularly as antiretroviral, agents, and can be used either alone or together with other compounds used in AIDS treatment such as AZT and/or protease inhibitors, for the treatment of HIV-infection, AIDS and manifestations of AIDS such as Kaposi sarcoma. Particularly preferred compounds are aminoglycoside-arginine conjugates in which the saccharide is a natural aminoglycoside antibiotic such as kanamycin, gentamycin and neomycin that is conjugated to arginine residues.