27780-71-8

Basic information

• Product Name: Benzoic acid, 4-[(3,7-dimethyl-2,6-octadienyl)oxy]-
• CAS NO: 27780-71-8
• Molecular Formula: C17H22O3
• Molecular Weight: 274.36
• Mol File: 27780-71-8.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 4-[(3,7-dimethyl-2,6-octadienyl)oxy]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 4-[(3,7-dimethyl-2,6-octadienyl)oxy]-(27780-71-8)
• EPA Substance Registry System: Benzoic acid, 4-[(3,7-dimethyl-2,6-octadienyl)oxy]-(27780-71-8)

Safety Data

• Hazardous Substances Data: 27780-71-8(Hazardous Substances Data)

Upstream product

• 4490-10-2 geranyl chloride 
• 99-76-3 methyl 4-hydroxylbenzoate 
• 6138-90-5 trans-geranyl bromide 
• 99-96-7 4-hydroxy-benzoic acid 
• 120-47-8 Ethyl 4-hydroxybenzoate 
• 60462-79-5 methyl geranyloxybenzoate 
• 29524-58-1 methyl 4-((3,7-dimethylocta-2,6-dien-1-yl)oxy)benzoate 
• 6138-90-5 geranyl bromide 

Downstream Products

• 1431978-37-8 methyl N²-(4-{[(2E)-3,7-dimethylocta-2,6-dienyl]oxy}benzoyl)-N⁵-[imino(2-oxido-2-oxohydrazino)methyl]-L-ornithinate 
• 60464-70-2 p-[(3,7-dimethyl-2,6-octadienyl)oxy]benzoic acid propargyl ester 
• 183583-80-4 N-(1,2-diethyltetrahydro-1H-pyrazol-4-yl)-4-[(2E)-3,7-diethyl-2,6-octadienyl]oxobenzamide 

Relevant articles and documents

2-Aryl benzazole derived new class of anti-tubercular compounds: Endowed to eradicate mycobacterium tuberculosis in replicating and non-replicating forms

The high mortality rate and the increasing prevalence of Mtb resistance are the major concerns for the Tuberculosis (TB) treatment in this century. To counteract the prevalence of Mtb resistance, we have synthesized 2-aryl benzazole based dual targeted molecules. Compound 9m and 9n were found to be equally active against replicating and non-replicating form of Mtb (MIC(MABA) 1.98 and 1.66 μg/ml; MIC(LORA) 2.06 and 1.59 μg/ml respectively). They arrested the cell division (replicating Mtb) by inhibiting the GTPase activity of FtsZ with IC50 values 45 and 64 μM respectively. They were also capable of kill Mtb in non-replicating form by inhibiting the biosynthesis of menaquinone which was substantiated by the MenG inhibition (IC50 = 11.62 and 7.49 μM respectively) followed by the Vit-K2 rescue study and ATP production assay.

Pyridine derivative, anti-ulcer drug, and antibacterial drug

A pyridine derivative or a salt thereof expressed by the following formula 1: STR1 wherein W represents a group expressed by the following formula 2 or formula 3; STR2 wherein R1 represents an alkenyloxy group; n represents 1 or 2; Ra represents a lower alkyl group; and Rb represents a halogen atom; and wherein each of R2 and R3 represents a hydrogen atom, a lower alkyl group, a lower alkoxy group, or halogenated alkyl group; Y represents a group expressed by --S--, --NH-- or --CONH--; m represents an integer of 0 to 2; and p represents 0 or 1. The pyridine derivative has an anti-ulcer effect or an antibacterial activity against Helicobacter pyroli to be available for prevention or cure of ulcers.

Alkylenediamine derivative, anti-ulcer drug, and antibacterial drug

An alkylenediamine derivative or a salt thereof expressed by the following formula 1: STR1 wherein each of R1 and R2 represents a lower alkyl group, and W represents a group expressed by any of the following formulas 2 and 3; STR2 wh