27792-82-1 Usage
Description
2,3-Dihydro-7-(hydroxymethyl)-1H-pyrrolizin-1-one is a necine base found in the EtOH extract of Urechites karwinskii roots. It is a chemical compound with a unique structure that can be manipulated through chemical reactions, such as reduction and oxidation, to produce different functional groups.
Uses
Used in Chemical Synthesis:
2,3-Dihydro-7-(hydroxymethyl)-1H-pyrrolizin-1-one is used as a starting material for the synthesis of various chemical compounds. The expression is: 2,3-Dihydro-7-(hydroxymethyl)-1H-pyrrolizin-1-one is used as a starting material for [chemical synthesis] for [its unique structure and reactivity].
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2,3-Dihydro-7-(hydroxymethyl)-1H-pyrrolizin-1-one is used as an intermediate in the development of new drugs. The expression is: 2,3-Dihydro-7-(hydroxymethyl)-1H-pyrrolizin-1-one is used as an intermediate for [drug development] for [its potential to be modified and incorporated into various drug molecules].
Used in Organic Chemistry Research:
2,3-Dihydro-7-(hydroxymethyl)-1H-pyrrolizin-1-one is also used in organic chemistry research to study the properties and reactions of necine bases and their derivatives. The expression is: 2,3-Dihydro-7-(hydroxymethyl)-1H-pyrrolizin-1-one is used as a subject of study for [organic chemistry research] for [its unique chemical properties and potential for various reactions].
References
Del Castillo et ai., Tetrahedron Lett., 1219 (1970)
Check Digit Verification of cas no
The CAS Registry Mumber 27792-82-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,7,7,9 and 2 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 27792-82:
(7*2)+(6*7)+(5*7)+(4*9)+(3*2)+(2*8)+(1*2)=151
151 % 10 = 1
So 27792-82-1 is a valid CAS Registry Number.
InChI:InChI=1/C8H9NO2/c10-5-6-1-3-9-4-2-7(11)8(6)9/h1,3,10H,2,4-5H2
27792-82-1Relevant articles and documents
Synthesis of 2,3-Dihydro-7-hydroxymethyl-1H-pyrrolizin-1-one, the Alkaloid Loroquine
Roeder, Erhard,Bartkowski, Jan-Pit Barko,Bourauel, Thomas
, p. 711 - 714 (2007/10/02)
The title compound 4 is synthesized in 8 steps by cyclization of N-tosylglycinate 5 with vinyl ketone 6.After elimination of water and sulfinic acid the pyrrolecarboxylate 9 is obtained which, on N-alkylation with ethyl acrylate, Dieckmann cyclization, saponification and decarboxylation, yields methylloroquine 12.The reaction with chlorotrimethylsilane/sulfuric acid in acetic anhydride and subsequent saponification gave loroquine (4) in 2.1 percent overall yiels.Key Words: Pheromones / Pyrrolizidine alkaloids / Pyrrolizine / Alkaloids
