27808-55-5 Usage
Description
[1,2,5]Oxadiazolo[3,4-b]pyridine, 5-methyl-, 3-oxide is a heterocyclic organic compound characterized by a molecular formula of C7H6N4O2. It features a unique structure with a fused five-membered oxadiazole and pyridine ring. [1,2,5]Oxadiazolo[3,4-b]pyridine, 5-methyl-, 3-oxide is distinguished by the presence of a methyl group on the fifth carbon of the oxadiazole ring and an oxygen atom at the third position of the pyridine ring. Due to its chemical properties and potential pharmacological and biological activities, it has garnered interest in the fields of medicinal chemistry and drug development.
Uses
Used in Pharmaceutical Industry:
[1,2,5]Oxadiazolo[3,4-b]pyridine, 5-methyl-, 3-oxide is used as a key intermediate compound for the synthesis of various pharmaceuticals. Its unique structure and potential biological activities make it a promising candidate for the development of new drugs targeting a range of medical conditions.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, [1,2,5]Oxadiazolo[3,4-b]pyridine, 5-methyl-, 3-oxide serves as a valuable research tool. Scientists can use this compound to study its interactions with biological targets, such as enzymes and receptors, which can provide insights into the development of novel therapeutic agents.
Used in Drug Development:
[1,2,5]Oxadiazolo[3,4-b]pyridine, 5-methyl-, 3-oxide's potential pharmacological properties make it a candidate for drug development. Researchers can explore its efficacy and safety in preclinical and clinical trials to determine its suitability as a therapeutic agent for specific medical conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 27808-55-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,7,8,0 and 8 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 27808-55:
(7*2)+(6*7)+(5*8)+(4*0)+(3*8)+(2*5)+(1*5)=135
135 % 10 = 5
So 27808-55-5 is a valid CAS Registry Number.
27808-55-5Relevant articles and documents
Furoxan rearrangement of some pyridofuroxan derivatives studied by 1H, 13C, 14N, 15N and 17O NMR spectroscopy
Cmoch,Kamienski,Kamienska-Trela,Stefaniak,Webb
, p. 480 - 488 (2007/10/03)
Pyridofuroxan ([1,2,5]oxodiazolo[3,4-b]pyridine 1-oxide) undergoes isomerization between the N1-oxide and N3-oxide forms which can be observed by the 1H, 13C and 15N NMR spectroscopy but not by 14N and 17O NMR at ambient and low temperatures. The rearrangement becomes slower at low temperatures and at 233 K 1H NMR signals for the two structures become observable. 1H, 13C and 15N chemical shifts and 1H-1H, 13C-1H and 13C-13C coupling constants are used to characterize both forms in the equilibrium mixture. From the 1H NMR integrals at 233 K equilibrium constants are calculated. Protonation studies using trifluoroacetic acid as a solvent showed the favoured site of protonation to be the pyridine N4 nitrogen atom. DFT shielding calculations are reported for the 13C, 15N and 17O nuclei which support the assignments given. From the point of view of structural changes, 1JCC data for 8-nitrotetrazolo[1,5-a]pyridine and o-nitroaminopyridine as precursors of the pyridofuroxans are given for comparison purposes. X-ray diffraction data on 5-methoxypyridofuroxan support the structural results obtained from the NMR investigations. Copyright
