27828-56-4Relevant articles and documents
Experimental study of bimolecular reaction kinetics in porous media
Kapoor,Raje
, p. 1234 - 1239 (2000)
A biomolecular reaction (1,2-naphthoquinone-4-sulfonic acid + aniline → 1,2-naphthoquinone-4-aminobenzene) in a saturated porous media flow in a column was studied to experimentally demonstrate the importance of reactant segregation in porous media flow.
Discovery of naphtho[1,2-d]oxazole derivatives as potential anti-HCV agents through inducing heme oxygenase-1 expression
Tseng, Chih-Hua,Lin, Chun-Kuang,Chen, Yeh-Long,Tseng, Chin-Kai,Lee, Jar-Yu,Lee, Jin-Ching
, p. 970 - 982 (2017/12/15)
A number of naphtho[1,2-d]oxazole derivatives were synthesized and evaluated for their anti-HCV virus activity. Among them, compound 18 was the most active, exhibited approximately 21-folds more active anti-HCV activity (IC50 of 0.63 μM) than t
O-Iodoxybenzoic Acid-Initiated One-Pot Synthesis of 4-Arylthio-1,2-naphthoquinones, 4-Arylthio-1,2-diacetoxynaphthalenes, and 5-Arylthio-/5-Aminobenzo[a]phenazines
Mishra, Abhaya Kumar,Moorthy, Jarugu Narasimha
, p. 6472 - 6480 (2016/08/16)
1,2-Naphthoquiones and their derivatives constitute an important category of compounds of relevance in pharmaceutical and material chemistry. It is shown that 1,2-naphthoquinones generated by o-iodoxybenzoic acid-mediated oxidation of 2-naphthols can be subjected to a cascade of reactions, namely oxidation, Michael addition, reduction, acetylation, and cyclocondensation, in the same pot to afford diverse 4-arylthio-1,2-naphthoquinones 2, 4-arylthio-1,2-diacetoxynaphthalenes 3, and 5-arylthio-/5-aminobenzo[a]phenazines 4 in very good isolated yields. The multistep single-pot synthesis occurs smoothly in DMF at rt.