27839-91-4

Basic information

• Product Name: 1-Propanone, 1-phenyl-2-(phenylsulfonyl)-
• CAS NO: 27839-91-4
• Molecular Formula: C15H14O3S
• Molecular Weight: 274.34
• Mol File: 27839-91-4.mol
• Article Data: 21

Chemical Properties

• CAS DataBase Reference: 1-Propanone, 1-phenyl-2-(phenylsulfonyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Propanone, 1-phenyl-2-(phenylsulfonyl)-(27839-91-4)
• EPA Substance Registry System: 1-Propanone, 1-phenyl-2-(phenylsulfonyl)-(27839-91-4)

Safety Data

• Hazardous Substances Data: 27839-91-4(Hazardous Substances Data)

Upstream product

• 28403-86-3 1-phenyl-2-(phenylthio)propan-1-one 
• 873-66-5 1-propenylbenzene 
• 618-41-7 Benzenesulfinic acid 
• 637-50-3 1-phenylpropene 
• 108-98-5 thiophenol 
• 3127-67-1 2-phenyl-but-2-enoic acid 
• 1212-08-4 S-Phenyl benzenethiosulfonate 
• 2114-00-3 2-bromo-1-phenyl-1-propanone 
• 873-55-2 sodium benzenesulfonate 
• 2114-03-6 2,2-dibromo-1-phenylpropan-1-one 
• 93-55-0 1-phenyl-propan-1-one 
• 108-86-1 bromobenzene 
• 93-54-9 1-Phenyl-1-propanol 
• 515-42-4 sodium phenylsulfonate 

Downstream Products

• 13557-25-0 1-(1-chloroethyl)phenyl sulfone 
• 38009-93-7 α-bromoethyl phenyl sulfone 
• 93-55-0 1-phenyl-propan-1-one 
• 882-33-7 diphenyldisulfane 
• 1130816-53-3 (1R,2S)-1-phenyl-2-(phenylsulfonyl)propan-1-ol 
• 117841-12-0 threo-2-chloro-1-phenyl-2-phenylsulfonylpropanol 
• 117841-12-0 erythro-2-chloro-1-phenyl-2-phenylsulfonylpropanol 
• 76380-14-8 phenyl 2-propenyl sulfone 
• 117841-14-2 2-chloro-2-(phenylsulfonyl)-1-phenylpropanone 

Relevant articles and documents

Hypervalent iodine in synthesis. 66. One pot preparation of β-keto sulfones by reaction of ketones, [hydroxy(tosyloxy) iodo] benzene, and sodium sulfinates

One pot reactions of ketones, [hydroxy(tosyloxy)iodo] benzene and sodium sulfinates lead to the formation of the corresponding β-keto sulfones under mild conditions and in good yield.

Oxidative Sulfonylation of Hydrazones Enabled by Synergistic Copper/Silver Catalysis

A copper/silver-cocatalyzed protocol for oxidative sulfonylation of hydrazones is demonstrated. A wide range of β-ketosulfones and N-acylsulfonamides are directly synthesized in moderate to good yields. Our work provides a viable method for scalable preparation of β-ketosulfone derivatives that have found wide applications in the pharmaceutical industry.

Method for synthesizing alpha-sulfone ketone compound from alpha, alpha-dibromo ketone by one-pot process

The invention discloses a method for synthesizing a high-added-value alpha-sulfone ketone compound from an alpha, alpha-dibromo ketone compound by a one-pot process. The method has the advantages thatan alpha-sulfone ketone derivative is synthesized from alpha, alpha-dibromo ketone, which is simple and easy to obtain, by the one-pot process without separation of an alpha-bromo ketone intermediate, so that a separation process for an intermediate product is omitted, the steps are reduced, and requirements for environment protection are met; the steps of the method are simple and easy to operate, no transition metal reagents are required, and economical sulfonate with less pollution is directly used as a promoter and a sulfonating agent for reducing debromination of the alpha, alpha-dibromoketone, so that the cost is reduced, and economic benefits of reactions are increased; a system for preparing the alpha-sulfone ketone derivative by the one-pot process is developed to provide a novel synthesis method for preparation of the alpha-sulfone ketone compound, and the method has good industrialization prospect and potential application value.