27851-29-2Relevant articles and documents
Synthesis and conformational analysis of D-gluco-pyranosyl-(6,6′)-D-gluco-pyranuronate, a model compound for the inter-glycan 6,6′-ester linkage
Hackbusch, Sven,Watson, Amelia,Franz, Andreas H.
, p. 1 - 12 (2018)
The synthesis of a 6,6′-ester linked disaccharide analog model compound was achieved in five steps from D-glucose and featured a key oxidative esterification transformation. The synthesized D-gluco-pyranosyl-(6,6′)-D-gluco-pyranuronate was characterized in D2O using NMR spectroscopy. Using the experimental data together with molecular dynamics simulations (TIP3P, water), a model of the compound's conformational behavior was established. The effect of the 6,6′-ester linkage on the solution phase structure was compared to that of the previously reported 6,6′-ether linkage in a disaccharide analog. Based on the established models, the ester linkage was found to have a profound effect on the overall shape of the molecule.
New class of alkynyl glycoside analogues as tyrosinase inhibitors
Saehlim, Natthiya,Athipornchai, Anan,Sirion, Uthaiwan,Saeeng, Rungnapha
supporting information, (2020/06/01)
A new series of alkynyl glycoside analogues were designed and synthesized from cheap and a commercially available sugar by introduction of various alkynyl and alkyl groups at C-1 and C-6 positions of the sugar ring. The inhibitory abilities of alkynyl gly
Electrochemical assay to detect influenza viruses and measure drug susceptibility
Zhang, Xiaohu,Dhawane, Abasaheb N.,Sweeney, Joyce,He, Yun,Vasireddi, Mugdha,Iyer, Suri S.
, p. 5929 - 5932 (2015/05/13)
An electrochemical assay has been designed to rapidly diagnose influenza viruses. Exposure of a glucose-bearing substrate to influenza viruses or its enzyme, neuraminidase (NA), releases glucose, which was detected amperometrically. Two methods were used