27869-54-1

Basic information

• Product Name: Benzeneacetonitrile, a-(1-naphthalenylmethylene)-, (Z)-
• CAS NO: 27869-54-1
• Molecular Formula: C19H13N
• Molecular Weight: 255.319
• Mol File: 27869-54-1.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Benzeneacetonitrile, a-(1-naphthalenylmethylene)-, (Z)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneacetonitrile, a-(1-naphthalenylmethylene)-, (Z)-(27869-54-1)
• EPA Substance Registry System: Benzeneacetonitrile, a-(1-naphthalenylmethylene)-, (Z)-(27869-54-1)

Safety Data

• Hazardous Substances Data: 27869-54-1(Hazardous Substances Data)

Upstream product

• 140-29-4 phenylacetonitrile 
• 66-77-3 1-naphthaldehyde 
• 4780-79-4 1-naphthalene methanol 

Downstream Products

• 72035-50-8 3-(naphthalen-1-yl)-2-phenylpropanenitrile 

Relevant articles and documents

Pyrenedione-Catalyzed α-Olefination of Nitriles under Visible-Light Photoredox Conditions

Herein, we report a combination of pyrenedione (PD) and KOtBu to achieve facile alcohol dehydrogenation under visible-light excitation, where aerobic oxygen is utilized as the terminal oxidant. The resulting carbonyl compound can be easily converted to vinyl nitriles in a single-pot reaction, at 60 °C in 6-8 h. This environmentally benign, organocatalytic approach has distinct advantages over transition-metal-catalyzed α-olefination of nitriles, which often operate at a significantly higher temperature for an extended reaction time.

Magnetic nanoparticle supported amine: An efficient and environmental benign catalyst for versatile Knoevenagel condensation under ultrasound irradiation

Amine functionalized silica coated Fe3O4 nanoparticles (SiO2@MNP-A) were successfully prepared as a novel heterogeneous amine. The catalyst was characterized by XRD, FT-IR, TEM, magnetic measurement, elemental analysis and was found to be a magnetically separable and highly active catalyst for ambient Knoevenagel condensation of aromatic aldehydes and a-aromatic (heteroaromatic or polyaromatic)-substituted methylene compounds in water under ultrasonic irradiation to afford the corresponding products in good to excellent yields. Very interestingly, SiO2@MNP-A successfully catalyze the reaction of the non-cyano substituted compound with benzaldehyde to achieve a key intermediate for the preparation of Atorvastatin calcium in green and atom-economic manner. In addition, the catalyst SiO2@MNP-A can be reused for 8 times without any obvious loss of its activity. The role of ultrasonication in the Knoevenagel condensation was also discussed with the assistance of UV-vis spectrometry.

Water-soluble calixarenes as new inverse phase-transfer catalysts. Their application to aldol-type condensation and Michael addition reactions in water

Aldol-type condensation and Michael addition reactions of activated methyl and methylene compounds in aqueous NaOH solution have been developed without the need for any added organic solvents. The water-soluble calix[n]arenes, which contain trimethylammon