27872-70-4

Basic information

• Product Name: 3-Pentanone, 2-(phenylthio)-
• CAS NO: 27872-70-4
• Molecular Formula: C11H14OS
• Molecular Weight: 194.298
• Mol File: 27872-70-4.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 3-Pentanone, 2-(phenylthio)-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Pentanone, 2-(phenylthio)-(27872-70-4)
• EPA Substance Registry System: 3-Pentanone, 2-(phenylthio)-(27872-70-4)

Safety Data

• Hazardous Substances Data: 27872-70-4(Hazardous Substances Data)

Upstream product

• 96-22-0 pentan-3-one 
• 17042-21-6 2-chloro-3-pentanone 
• 108-98-5 thiophenol 
• 52322-54-0 2-(phenylthio)benzo[d]isothiazol-3(2H)-one 1,1-dioxide 
• 51425-54-8 (Z)-3-trimethylsiloxy-2-pentene 
• 882-33-7 diphenyldisulfane 
• 4187-86-4 pent-1-yn-3-ol 
• 13307-56-7 1,1-bis(phenylthio)ethane 
• 931-59-9 benzenesulfenyl chloride 
• 17042-24-9 2-mercapto-pentan-3-one 
• 100-34-5 benzene diazonium chloride 
• 815-52-1 2-bromopentan-3-one 
• 51425-53-7 (E)-3-[(trimethylsilyl)oxy]pent-2-ene 
• 66303-47-7 (2-Chloro-2-ethoxy-ethylsulfanyl)-benzene 

Downstream Products

• 1896-62-4 (E)-benzalacetone 
• 113503-13-2 2-(phenylmethylsulfonio)-3-pentanone triflate 
• 55834-35-0 4-methyl-4-(phenylthio)hept-6-en-3-one 
• 55834-34-9 4-methyl-4-phenylsulfanyl-octan-3-one 
• 96-22-0 pentan-3-one 
• 882-33-7 diphenyldisulfane 

Relevant articles and documents

Synthesis and reactivity of α-sulfenyl-β-chloroenones, including oxidation and Stille cross-coupling to form chalcone derivatives

The synthesis of a range of novel α-sulfenyl-β-chloroenones from the corresponding α-sulfenylketones, via a NCS mediated chlorination cascade, is described. The scope of the reaction has been investigated and compounds bearing alkyl- and arylthio substituents have been synthesised. In most instances, the Z α-sulfenyl-β-chloroenones were formed as the major products, while variation of the substituent at the β-carbon position led to an alteration in stereoselectivity. Stille cross-coupling with the Z α-sulfenyl-β-chloroenones led to selective formation of Z sulfenyl chalcones, while the E α-sulfenyl-β-chloroenones did not react under the same conditions. Oxidation of the Z α-sulfenyl-β-chloroenones was followed by isomerisation, leading to the E α-sulfinyl-β-chloroenones. Stille cross-coupling with the E α-sulfinyl-β-chloroenones produced the E sulfinyl chalcones. Either the E or Z sulfinyl chalcones can be obtained by altering the sequence of oxidation and Stille cross-coupling.

α-Organylchalcogenation of aldehydes and ketones with diorganyl dichalcogenides promoted by K3PO4

A new catalytic method for direct α-organylchalcogenation of aldehydes and ketones has been developed. When various aldehydes and ketones were allowed to react with diorganyl dichalcogenides in the presence of K 3PO4, under mild reac

N-Chlorosuccinimide as a versatile reagent for the sulfenylation of ketones: a facile synthesis of α-ketothioethers

The sulfenylation of ketones having α-hydrogens has been achieved using N-chlorosuccinimide (NCS) under mild reaction conditions to produce α-ketothioethers in excellent yields with high selectivity. The use of NCS makes this method quite simple, convenient and practical.