27970-50-9 Usage
Description
3-N-Pentyl-2,4-pentanedione, also known as 3-(n-Amyl)-2,4-pentanedione, is an organic compound with the molecular formula C10H18O2. It is a colorless to pale yellow liquid with a fruity odor. 3-N-PENTYL-2,4-PENTANEDIONE is characterized by its unique chemical structure, which consists of a diketone group (two carbonyl groups) and a pentyl chain attached to the third carbon.
Uses
Used in Pharmaceutical Industry:
3-N-Pentyl-2,4-pentanedione is used as a reagent for the synthesis of thiazolidin-4-ones, which are known as HIV-1 reverse transcriptase inhibitors. These inhibitors play a crucial role in the development of antiretroviral drugs, as they help in the treatment and management of HIV/AIDS by blocking the replication of the virus.
In the synthesis process, 3-N-pentyl-2,4-pentanedione serves as a key intermediate, contributing to the formation of the thiazolidin-4-one ring structure. The compound's diketone functionality is particularly important, as it allows for the formation of the desired ring through a series of chemical reactions.
The use of 3-N-pentyl-2,4-pentanedione in the pharmaceutical industry highlights its potential as a valuable compound in the development of life-saving medications. Its role in the synthesis of HIV-1 reverse transcriptase inhibitors demonstrates its importance in the ongoing fight against HIV/AIDS and contributes to the advancement of medical research in this field.
Check Digit Verification of cas no
The CAS Registry Mumber 27970-50-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,7,9,7 and 0 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 27970-50:
(7*2)+(6*7)+(5*9)+(4*7)+(3*0)+(2*5)+(1*0)=139
139 % 10 = 9
So 27970-50-9 is a valid CAS Registry Number.
InChI:InChI=1/C10H18O2/c1-4-5-6-7-10(8(2)11)9(3)12/h10H,4-7H2,1-3H3
27970-50-9Relevant articles and documents
Synthesis and Properties of 4,6-Dimethyl-5-pentyl-2-thioxo-1,2-dihydropyridine-3-carbonitrile and 3-Amino-4,6-dimethyl-5-pentylthieno[2,3-b]pyridines
Buryi,Dotsenko,Aksenov,Aksenova,Krivokolysko,Dyadyuchenko
, p. 1575 - 1585 (2019)
The reaction of 3-pentylpentane-2,4-dione with cyanothioacetamide afforded 4,6-dimethyl-5-pentyl-2-thioxo-1,2-dihydropyridine-3-carbonitrile. Alkylation of the latter led to the formation of 2-alkylsulfanyl-4,6-dimethyl-5-pentylpyridine-3-carbonitriles or 3-amino-4,6-dimethyl-5-pentylthieno[2,3-b]pyridines, depending on the alkylating agent and reaction conditions. The structures of the key compounds were proved by 2D NMR spectroscopy and X-ray analysis. Biological activity of the synthesized compounds was evaluated in silico. Some compounds were experimentally found to stimulate growth of sunflower seedlings.
