27975-78-6

Basic information

• Product Name: 1-PHENYL-1-PENTYN-3-OL
• Synonyms: TIMTEC-BB SBB008984;1-PHENYL-1-PENTYN-3-OL;1-Pentyn-3-ol,1-phenyl-;1-phenylpent-1-yn-3-ol
• CAS NO: 27975-78-6
• Molecular Formula: C₁₁H₁₂O
• Molecular Weight: 160.21
• Product Categories: Alkynes;Internal;Organic Building Blocks
• Mol File: 27975-78-6.mol
• Article Data: 66

Chemical Properties

• Boiling Point: 266.909 °C at 760 mmHg
• Flash Point: 110 °C
• Appearance: /
• Density: 1.336 g/mL at 25 °C
• Vapor Pressure: 0.004mmHg at 25°C
• Refractive Index: n20/D 1.559
• CAS DataBase Reference: 1-PHENYL-1-PENTYN-3-OL(CAS DataBase Reference)
• NIST Chemistry Reference: 1-PHENYL-1-PENTYN-3-OL(27975-78-6)
• EPA Substance Registry System: 1-PHENYL-1-PENTYN-3-OL(27975-78-6)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• WGK Germany: 3
• Hazardous Substances Data: 27975-78-6(Hazardous Substances Data)

Usage

Description

1-PHENYL-1-PENTYN-3-OL is an organic compound with the molecular formula C11H12O. It is characterized by the presence of a phenyl group, a pentyn-3-ol chain, and a hydroxyl group. 1-PHENYL-1-PENTYN-3-OL is known for its unique chemical properties and potential applications in various industries.

Uses

Used in Chemical Synthesis:
1-PHENYL-1-PENTYN-3-OL is used as a reactant in the heterogeneously catalyzed etherification of glycerol. This process involves the reaction of glycerol with an alcohol or phenol in the presence of a catalyst to form ethers, which are valuable intermediates in the chemical industry.
Used in Organic Chemistry:
1-PHENYL-1-PENTYN-3-OL is also utilized in the Fritsch-Wiechell rearrangement of 1-chlorovinyl sulfoxides. This rearrangement is a chemical reaction that involves the conversion of 1-chlorovinyl sulfoxides to α-chloro carbonyl compounds, which are important building blocks for the synthesis of various organic compounds.

InChI:InChI=1/C11H12O/c1-2-11(12)9-8-10-6-4-3-5-7-10/h3-7,11-12H,2H2,1H3

Upstream product

• 2579-22-8 Phenylpropargyl aldehyde 
• 925-90-6 ethylmagnesium bromide 
• 123-38-6 propionaldehyde 
• 536-74-3 phenylacetylene 
• 27975-81-1 (+/-)-(3-bromopent-1-ynyl)benzene 
• 137469-63-7 C₂₃H₂₂O₂Se₂ 
• 62459-78-3 9-Phenylethynyl-9-bora-bicyclo[3.3.1]nonane 
• 2700-30-3 N,N-diisorpopylformamide 
• 4250-81-1 1-phenyl-1-pentyne 
• 7205-94-9 chloromethyl phenyl sulfoxide 
• 128867-15-2 2-Benzenesulfinyl-2-chloro-1-phenyl-ethanol 
• 134905-02-5 C₂₃H₂₂Se₂ 
• 1004-22-4 (phenylethynyl)sodium 
• 4187-86-4 pent-1-yn-3-ol 

Downstream Products

• 19307-74-5 1-phenyl-pent-1-yn-3-one 
• 117983-72-9 chloromethyl 1-phenyl-1-pentyn-3-yl ether 
• 15295-30-4 5,5-Diphenyl-penten-⁽⁴⁾-ol-⁽³⁾ 
• 104581-57-9 5,5-diphenylpent-4-en-3-one 
• 104581-54-6 (Z)-1,2-Diphenyl-pent-1-en-3-ol 
• 93247-40-6 (1-tert-Butyl-penta-1,2-dienyl)-benzene 
• 75031-47-9 2-phenyl-2,3-hexadiene 
• 124974-83-0 2-Ethyl-4-phenyl-3-butynenitrile 
• 3152-68-9 (1E)-1-phenylpent-1-en-3-one 
• 105836-17-7 (R)-1-phenyl-3-pentanol 
• 71747-37-0 (S)-1-phenylpentan-3-ol 
• 59403-00-8 2,2,2-Trichloro-acetimidic acid 1-ethyl-3-phenyl-prop-2-ynyl ester 
• 93247-39-3 (1-Cyclohexyl-penta-1,2-dienyl)-benzene 
• 93247-41-7 (1-Allyl-penta-1,2-dienyl)-benzene 

Relevant articles and documents

Cascade Radical Cyclization on Alkynyl Vinylogous Carbonates for the Divergent Synthesis of Tetrasubstituted Furans and Dihydrofurans

A single alkynyl vinylogous carbonate was elaborated to tetrasubstituted furan or dihydrofuran via a cascade inter-intramolecular radical reaction by changing the radical being added. The strategy could be used in the synthesis of polycyclic heterocycles as well as bis-furan exhibiting atropisomerism. Installation of a new furan motif on the existing one was feasible by iteration. Stannyl dihydrofuran derivative was used in Stille coupling, whereas intramolecular Friedel-Crafts acylation on the furan gave furanonaphthol.

A boron-oxygen transborylation strategy for a catalytic midland reduction

The enantioselective hydroboration of ketones is a textbook reaction requiring stoichiometric amounts of an enantioenriched borane, with the Midland reduction being a seminal example. Here, a turnover strategy for asymmetric catalysis, boron.oxygen transb

Catalytic Ynone-Amidine Formal [4 + 2]-Cycloaddition for the Regioselective Synthesis of Tricyclic Azepines

A Ca(OTf)2- and self-promoted ynone-amidine atom-economic formal [4 + 2]-cycloaddition of various ynones with amidines is reported for the construction of highly functionalized tricyclic azepines. High reaction rate, ease of operation, and high product se