27992-31-0

Basic information

• Product Name: 5,6-DIMETHYL-1H-PYRIDIN-2-ONE
• Synonyms: 5,6-DIMETHYL-1H-PYRIDIN-2-ONE;5,6-dimethyl-2-pyridone;5,6-Dimethylpyridin-2(1H)-one;5,6-dimethyl-2(1H)-pyridinone(SALTDATA: FREE);5,6-dimethyl-2(1H)-pyridinone
• CAS NO: 27992-31-0
• Molecular Formula: C₇H₉NO
• Molecular Weight: 123.15246
• EINECS: 248-767-2
• Mol File: 27992-31-0.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 299.7°Cat760mmHg
• Flash Point: 169.6°C
• Appearance: /
• Density: 1.013g/cm³
• Vapor Pressure: 0.00117mmHg at 25°C
• Refractive Index: 1.49
• CAS DataBase Reference: 5,6-DIMETHYL-1H-PYRIDIN-2-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 5,6-DIMETHYL-1H-PYRIDIN-2-ONE(27992-31-0)
• EPA Substance Registry System: 5,6-DIMETHYL-1H-PYRIDIN-2-ONE(27992-31-0)

Safety Data

• Hazardous Substances Data: 27992-31-0(Hazardous Substances Data)

Usage

General Description

5,6-DIMETHYL-1H-PYRIDIN-2-ONE, also known as 2,6-dimethyl-2-pyridone, is a chemical compound with the molecular formula C7H9NO. It is a derivative of pyridine and is commonly used as a building block in organic synthesis. 5,6-DIMETHYL-1H-PYRIDIN-2-ONE is a colorless liquid with a boiling point of 218°C and a molecular weight of 123.153 g/mol. It is used in the production of pharmaceuticals, agrochemicals, and other specialty chemicals. 5,6-DIMETHYL-1H-PYRIDIN-2-ONE has potential applications in a wide range of industries and is known for its versatility as a chemical intermediate.

InChI:InChI=1/C7H9NO/c1-5-3-4-7(9)8-6(5)2/h3-4H,1-2H3,(H,8,9)

Upstream product

• 72716-80-4 2-hydroxy-5,6-dimethylnicotinonitrile 
• 51727-05-0 5,6-dimethyl-2-hydroxynicotinic acid 
• 22428-91-7 2-methyl-3-oxobutanal 
• 58483-99-1 2-amino-5,6-dimethyl-nicotinamide 
• 90007-21-9 2-hydroxy-5,6-dimethyl-nicotinic acid amide 
• 52648-22-3 3,4-dihydro-5,6-dimethyl-2(1H)-pyridone 
• 72716-80-4 1,2-dihydro-5,6-dimethyl-2-oxo-3-pyridinecarbonitrile 
• 10413-01-1 4-methyl-5-oxo-hexanenitrile 
• 132247-74-6 (E)-4-hydroxy-3-methylbut-3-en-2-one sodium salt 

Downstream Products

• 99934-42-6 2,3-Dimethyl-6-phenoxy-pyridine 
• 99934-33-5 (1S,8R)-8,12-Dimethyl-9-aza-tricyclo[6.2.2.0^2,7]dodeca-2⁽⁷⁾,3,5,11-tetraen-10-one 
• 98276-88-1 3-nitro-5,6-dimethyl-2(1H)-pyridinone 
• 80675-99-6 exo-N-phenyl-3,4,8-trimethyl-8-aza-7-oxobicyclo<2.2.2>oct-4-ene-1,2-dicarboximide 
• 248247-85-0 3-amino-5,6-dimethyl-4-(3-methylbenzoyl)pyridin-2(1H)-one 
• 248247-23-6 3-amino-4-(3,5-dimethyl-benzyl)-5,6-dimethyl-1H-pyridin-2-one 
• 847741-01-9 N-[4-((3-methylphenyl)hydroxymethyl)-2-methoxy-5,6-dimethylpyridin-3-yl]-2,2-dimethylpropionamide 
• 847741-02-0 N-[2-methoxy-5,6-dimethyl-4-(3-methylbenzoyl)pyridin-3-yl]-2,2-dimethylpropionamide 
• 858338-82-6 N-[4-(3,5-dimethyl-benzyl)-2-methoxy-5,6-dimethyl-pyridin-3-yl]-2,2-dimethyl-propionamide 
• 65213-96-9 2,3-dimethyl-6-chloro-5-nitropyridine 
• 583-61-9 2,3-Lutidine 
• 441304-12-7 5,6-dimethyl-3-[[ethoxy(thiocarbonyl)]thio]-2-methoxypyridine 

Relevant articles and documents

PYRIDINE DERIVATIVES AND THEIR USE AS MEDICAMENTS FOR TREATING DISEASES RELATED TO MCH RECEPTOR

The present invention encompasses novel substituted pyridine compounds of Formula (I), which act as MCH receptor antagonists. These compositions and pharmaceutical compositions thereof are useful in the prophylaxis or treatment of improving memory function, sleeping and arousal, anxiety, depression, mood disorders, seizure, obesity, diabetes, appetite and eating disorders, cardiovascular disease, hypertension, dyslipidemia, myocardial infarction, binge eating disorders including bulimia, anorexia, mental disorders including manic depression, schizophrenia, delirium, dementia, stress, cognitive disorders, attention deficit disorder, substance abuse disorders and dyskinesias including Parkinson's disease, epilepsy, and addiction.

ANTIPRURITICS

It is intended to provide antipruritics (drugs to control itching, antiitch agents and drugs to stop itching). It is found out that a compound having an agonistic activity to the cannabinoid receptor shows an antipruritics effect.

Preparation and Reaction of Pyridones: Steric and Electronic Effects on Cycloadditions with 2(1H)-Pyridones

The reactions of series of substituted 2(1H)-pyridones with dimethyl butynedioate have been studied.Cycloadditions across the 3,6-positions can be observed in certain instances and are particularly favoured where steric buttressing occurs between the substituent groups of the starting pyridones.The pyridone could not be induced to react with simple olefins, either by intermolecular or, via incorporation of alkenyl substituents, by intramolecular processes.From the results it is shown that 2-pyridones can be encouraged to behave as reactive classical dienes in cycloaddition reactions.