280-70-6Relevant articles and documents
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Lambert et al.
, p. 3761,3762,3763,3765-3767 (1967)
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Concise syntheses of bridged morpholines
Zaytsev, Andrey V.,Pickles, James E.,Harnor, Suzannah J.,Henderson, Alistair P.,Alyasiri, Mohammed,Waddell, Paul G.,Cano, Celine,Griffin, Roger J.,Golding, Bernard T.
, p. 53955 - 53957 (2016/07/06)
Concise and practical syntheses of 8-oxa-3-aza-bicyclo[3.2.1]octane and 9-oxa-3-aza-bicyclo[3.3.1]nonane are described starting from furan-2,5-dicarboxylic acid and 4H-pyran-2,6-dicarboxylic acid, respectively, and using a solvent-free step for a key cyclisation.
PROCESS FOR THE REDUCTIVE AMINATION OF ALDEHYDES AND KETONES VIA THE FORMATION OF MACROCYCLIC POLYIMINE INTERMEDIATES
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Page/Page column 18-19, (2008/06/13)
Aldehyde or ketone compounds having more than one carbonyl group are reductively aminated to form a product amine compound having more than one primary amino group. The aldehyde or ketone compound is reacted with the product amine compound, to form a reaction mixture that contains one or more intermediates. The intermediate is then reductively aminated to form the desired product. This process produces the desired product in very high yields with low levels of secondary amine impurities.