280120-06-1

Basic information

• Product Name: 1-(4-fluoro-3-cyano)phenyl-3-(ethoxycarbonyl)-4-azidopyrazole-5-carboxylic acid
• Synonyms: 1-(4-fluoro-3-cyano)phenyl-3-(ethoxycarbonyl)-4-azidopyrazole-5-carboxylic acid
• CAS NO: 280120-06-1
• Molecular Weight: 344.262
• Mol File: 280120-06-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-(4-fluoro-3-cyano)phenyl-3-(ethoxycarbonyl)-4-azidopyrazole-5-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-fluoro-3-cyano)phenyl-3-(ethoxycarbonyl)-4-azidopyrazole-5-carboxylic acid(280120-06-1)
• EPA Substance Registry System: 1-(4-fluoro-3-cyano)phenyl-3-(ethoxycarbonyl)-4-azidopyrazole-5-carboxylic acid(280120-06-1)

Safety Data

• Hazardous Substances Data: 280120-06-1(Hazardous Substances Data)

Upstream product

• 123-91-1 1,4-dioxane 
• 280120-05-0 3-Ethyl-5-methyl 1-(4-fluoro-3-cyano)phenyl-4-azidopyrazole-3,5-dicarboxylate 
• 53312-81-5 3-cyano-4-fluoroaniline 
• 17417-09-3 2-fluoro-5-nitrobenzonitrile 
• 280120-04-9 3-Ethyl-5-methyl 1-(4-fluoro-3-cyano)phenyl-4-aminopyrazole-3,5-dicarboxylate 
• 280120-03-8 cyano-[(3-cyano-4-fluoro-phenyl)-hydrazono]-acetic acid ethyl ester 

Downstream Products

• 280120-07-2 1-(3-cyano-4-fluoro-phenyl)-6-(2'-formyloxymethyl-biphenyl-4-yl)-7-oxo-6,7-dihydro-1H-pyrazolo[4,3-d]pyrimidine-3-carboxylic acid ethyl ester 
• 280117-57-9 1-(3-amino-benzo[d]isoxazol-5-yl)-6-(2'-hydroxymethyl-biphenyl-4-yl)-7-oxo-6,7-dihydro-1H-pyrazolo[4,3-d]pyrimidine-3-carboxylic acid ethyl ester 
• 280120-08-3 4-azido-5-[2'-(tert-butyl-dimethyl-silanyloxymethyl)-biphenyl-4-ylcarbamoyl]-1-(3-cyano-4-fluoro-phenyl)-1H-pyrazole-3-carboxylic acid ethyl ester 

Relevant articles and documents

Preparation of 1-(3-aminobenzo[d]isoxazol-5-yl)-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-ones as potent, selective, and efficacious inhibitors of coagulation factor Xa

Previously, potent factor Xa inhibitors were described based on the 1H-pyrazolo[4,3-d]pyrimidin-7(6H)-one bicyclic core and a 4-methoxyphenyl P1 moiety. This manuscript describes 1H-pyrazolo[4,3-d]pyrimidin-7(6H)-one and related bicyclic cores with the 3-