28020-37-3

Basic information

• Product Name: 2,6-DIMETHOXYPYRIDIN-3-AMINE
• Synonyms: 2,6-DIMETHOXYPYRIDIN-3-AMINE;2,6-Dimethoxypyridine-3-amine;2,6-Dimethoxy-3-pyridinamine;3-Amino-2,6-dimethoxypyridine;3-Pyridinamine, 2,6-dimethoxy-;3-Amino-2,6-dimethoxypyridine≥ 98% (GC)
• CAS NO: 28020-37-3
• Molecular Formula: C₇H₁₀N₂O₂
• Molecular Weight: 154.1665
• Product Categories: Pyridine series;Heterocycle-Pyridine series
• Mol File: 28020-37-3.mol
• Article Data: 3

Chemical Properties

• Melting Point: 43-45 °C
• Boiling Point: 265.705 °C at 760 mmHg
• Flash Point: 114.495 °C
• Appearance: /
• Density: 1.16 g/cm³
• Vapor Pressure: 0.00902mmHg at 25°C
• Refractive Index: 1.543
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 3.12±0.10(Predicted)
• CAS DataBase Reference: 2,6-DIMETHOXYPYRIDIN-3-AMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-DIMETHOXYPYRIDIN-3-AMINE(28020-37-3)
• EPA Substance Registry System: 2,6-DIMETHOXYPYRIDIN-3-AMINE(28020-37-3)

Safety Data

• Hazardous Substances Data: 28020-37-3(Hazardous Substances Data)

Usage

Chemical Properties

Brick red crystalline solid

InChI:InChI=1/C7H10N2O2/c1-10-6-4-3-5(8)7(9-6)11-2/h3-4H,8H2,1-2H3

Upstream product

• 80789-72-6 3-amino-2,6-dimethoxypyridine monohydrochloride 
• 6231-18-1 2,6-dimethoxypyridine 

Downstream Products

• 206192-70-3 methyl 3-(4-methoxy-benzenesulfonylamino)-2,6-dimethoxy-isonicotinate 
• 206192-71-4 methyl 3-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-2,6-dimethoxy-isonicotinate 
• 206192-72-5 3-[benzyl-(4-methoxy-benzenesulfonyl)-amino]-2,6-dimethoxy-isonicotinic acid 
• 286369-98-0 N-(2,6-Dimethoxy-3-pyridyl)-N'-{4-[(6,7-dimethoxy-4-quinolyl)oxy]-2,5-dimethylphenyl}urea 

Relevant articles and documents

Aromatic amine compound synthesis method

The invention discloses an aromatic amine compound synthesis method which is characterized in that the method is implemented according to any of two methods. The first method includes the steps: mixing an alkyl aromatic compound with a general formula (I) and a nitrogen-containing compound with a general formula (II); performing reaction on mixture under an oxidizing agent and an organic solvent to obtain an aromatic amine compound with a general formula (III). The second method includes the steps: mixing an aromatic alcohol derivative with a general formula (I') and the nitrogen-containing compound with the general formula (II); performing reaction on mixture under an acid additive and an organic solvent to prepare the aromatic amine compound with the general formula (III). According to the method, a lot of alkyl aromatic compounds or aromatic alcohol derivatives firstly serve as raw materials, and the raw materials are reacted to generate the aromatic amine compound without the action of metal catalysis. Compared with a traditional synthesis method, the synthesis method has the advantages that the method is high in yield and simple in condition, waste discharging amount is less,metal participation is omitted, a reaction device is simple, industrial production is easily achieved and the like. The method has a wide application prospect.

SUBSTITUTED TRIAZOLE DERIVATIVES AS OXYTOCIN ANTAGONISTS

The present invention relates to a class of substituted triazoles of formula (I) with activity as oxytoci antagonists, uses thereof, processes for the preparation thereof and compositions containing sai inhibitors. These inhibitors have utility in a variety of therapeutic areas including sexual dysfunction particularly premature ejaculation (P.E.).