28048-29-5 Usage
Description
(2-NITRO-PHENYL)-PROPYNOIC ACID ETHYL ESTER is a chemical compound with the molecular formula C11H9NO4. It is an ethyl ester derivative of the propynoic acid, containing a nitrophenyl group. (2-NITRO-PHENYL)-PROPYNOIC ACID ETHYL ESTER is characterized by its yellow crystalline appearance and is known for its various chemical and pharmaceutical applications. Its unique properties and reactivity make it a valuable component in reactions and synthesis processes. However, due to its potential hazards, it is crucial to handle this chemical with care and in accordance with proper safety measures.
Uses
Used in Chemical Synthesis:
(2-NITRO-PHENYL)-PROPYNOIC ACID ETHYL ESTER is used as a key intermediate in the synthesis of various organic compounds. Its reactivity and functional groups make it suitable for use in a wide range of chemical reactions, including esterification, amidation, and condensation reactions.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, (2-NITRO-PHENYL)-PROPYNOIC ACID ETHYL ESTER is used as a building block for the development of new drugs. Its unique structure and properties allow it to be incorporated into the design of novel therapeutic agents, potentially leading to the discovery of new treatments for various diseases and conditions.
Used in Research and Development:
(2-NITRO-PHENYL)-PROPYNOIC ACID ETHYL ESTER is also utilized in research and development settings, where it can be employed to study the properties and behavior of various chemical compounds. Its reactivity and functional groups make it an ideal candidate for use in experiments and investigations aimed at understanding the fundamental principles of organic chemistry.
Used in Material Science:
In the field of material science, (2-NITRO-PHENYL)-PROPYNOIC ACID ETHYL ESTER can be used to develop new materials with unique properties. Its incorporation into polymers, coatings, and other materials can lead to the creation of innovative products with enhanced performance characteristics.
Check Digit Verification of cas no
The CAS Registry Mumber 28048-29-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,8,0,4 and 8 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 28048-29:
(7*2)+(6*8)+(5*0)+(4*4)+(3*8)+(2*2)+(1*9)=115
115 % 10 = 5
So 28048-29-5 is a valid CAS Registry Number.
InChI:InChI=1/C11H9NO4/c1-2-16-11(13)8-7-9-5-3-4-6-10(9)12(14)15/h3-6H,2H2,1H3
28048-29-5Relevant articles and documents
trans Deformation of a Carbon-Carbon Triple Bond in Response to Incipient Nucleophilic Attack: the X-Ray Crystal Structure of Ethyl 3-(2-Nitrophenyl)propynoate at 150 K
Rice, Craig R.,Wallis, John D.
, p. 572 - 574 (1993)
In the title compound 1 the electron-deficient alkyne bond shows a pronounced trans distortion in response to an adjacent electron rich nitro O atom, suggesting that the more favourable reaction coordinate for addition of nucleophiles to activated alkynes involves trans rather than cis addition.
Synthesis of 3-arylindole-2-carboxylates via copper-catalyzed hydroarylation of o-nitrophenyl-substituted alkynoates and subsequent cadogan cyclization
Yamamoto, Yoshihiko,Yamada, Satoshi,Nishiyama, Hisao
supporting information; experimental part, p. 701 - 706 (2011/05/08)
A two-step route to biologically important 3-arylindole-2-carboxylic esters has been successfully established: o-nitrophenyl-substituted alkynoates underwent copper-catalyzed hydroarylation in the presence of commercially available arylboronic acids to afford 3,3-diarylacrylates, which were then converted to indolecarboxylates via a modified Cadogan cyclization using a molybdenum catalyst and triphenylphosphine. Copyright
