28049-63-0 Usage
Description
1-(2-fluorophenyl)cyclobutanecarbonitrile, with the molecular formula C11H8FN, is a white crystalline solid that serves as a crucial building block in the synthesis of pharmaceuticals and agrochemicals. This chemical compound is renowned for its versatility in undergoing various reactions, such as nucleophilic aromatic substitution, and is a valuable intermediate in the production of advanced materials. Its widespread use in academic and industrial research underscores its significance in the development of diverse biologically active compounds.
Uses
Used in Pharmaceutical Industry:
1-(2-fluorophenyl)cyclobutanecarbonitrile is used as a key building block for the synthesis of various pharmaceuticals. Its ability to undergo nucleophilic aromatic substitution and other reactions makes it a versatile compound in the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical industry, 1-(2-fluorophenyl)cyclobutanecarbonitrile is utilized as a starting material for the preparation of different agrochemicals. Its reactivity and structural properties contribute to the creation of compounds that can be used in the development of pesticides, herbicides, and other agricultural products to enhance crop protection and yield.
Used in Academic Research:
1-(2-fluorophenyl)cyclobutanecarbonitrile is employed as a valuable intermediate in academic research, where it is used to explore new reaction pathways and synthesize a wide range of biologically active compounds. Its application in research facilitates the discovery of novel chemical entities with potential applications in various fields, including medicine and agriculture.
Used in Industrial Research:
This chemical compound is also widely used in industrial research, where it serves as a crucial intermediate in the production of advanced materials. Its structural properties and reactivity make it an essential component in the development of new materials with improved properties, such as enhanced stability, reactivity, or selectivity, for various applications in different industries.
Check Digit Verification of cas no
The CAS Registry Mumber 28049-63-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,8,0,4 and 9 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 28049-63:
(7*2)+(6*8)+(5*0)+(4*4)+(3*9)+(2*6)+(1*3)=120
120 % 10 = 0
So 28049-63-0 is a valid CAS Registry Number.
28049-63-0Relevant articles and documents
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Butler,D.E.,Pollatz,J.C.
, p. 1308 - 1309 (1971)
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Oxadiazole Amine Derivative Compounds as Histone Deacetylase 6 Inhibitor, and the Pharmaceutical Composition Comprising the same
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Paragraph 0379-0382, (2017/07/18)
The present invention relates to a novel compound having an activity of inhibiting histone deacetylase 6 (HDAC6), an optical isomer thereof or a pharmaceutically acceptable salt thereof, a use thereof for preparation of a drug for treatment, a pharmaceutical composition comprising the same, a treatment method using the composition, and a method for preparing the same. The novel compound, an optical isomer thereof or a pharmaceutically acceptable salt thereof according to the present invention has an activity of inhibiting histone deacetylase 6 (HDAC6), and is effective for preventing or treating HDAC6-related diseases, including infectious diseases; neoplasm; endocrine, nutritional and metabolic diseases; mental and behavior disorders; nerve disorders; eye and adnexa diseases; cardiovascular diseases; respiratory diseases; digestive organ diseases; skin and subcutaneous tissue diseases; musculoskeletal and connective tissue diseases; or congenital malformation, deformation and chromosomal abnormality.COPYRIGHT KIPO 2017
NOVEL TRPV3 MODULATORS
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Page/Page column 38, (2012/03/09)
Disclosed herein are modulators of TRPV3 of formula (I), wherein G1, X1, X2, X3, X4, X5, G2, Z1, Ra, Rb, u, and p are as defined in the specifica
