280581-64-8 Usage
Description
(2-chloro-5-fluoro-pyrimidin-4-yl)-phenyl-amine is a chemical compound with the molecular formula C11H8ClFN4. It is a derivative of pyrimidine and aniline, containing a pyrimidinyl fluoro-chloro substituent and a phenyl-amine group. (2-chloro-5-fluoro-pyrimidin-4-yl)-phenyl-amine is known for its versatile properties and is commonly used as a building block in the synthesis of various pharmaceuticals and agrochemicals. Its structure and properties make it a valuable intermediate in the production of a wide range of biologically active compounds. The presence of the chloro and fluoro atoms in its structure also gives it potential for use as a pesticide or herbicide. Due to its versatile properties, (2-chloro-5-fluoro-pyrimidin-4-yl)-phenyl-amine is an important component in the chemical industry for the development of various products with pharmaceutical, agricultural, and biological applications.
Uses
Used in Pharmaceutical Industry:
(2-chloro-5-fluoro-pyrimidin-4-yl)-phenyl-amine is used as a building block for the synthesis of various pharmaceuticals. Its unique structure and properties make it a valuable intermediate in the production of biologically active compounds, contributing to the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
(2-chloro-5-fluoro-pyrimidin-4-yl)-phenyl-amine is used as a building block for the synthesis of various agrochemicals. Its potential as a pesticide or herbicide makes it a valuable component in the development of new agricultural products designed to protect crops and enhance yield.
Used in Chemical Industry:
(2-chloro-5-fluoro-pyrimidin-4-yl)-phenyl-amine is used as an important component in the chemical industry for the development of various products with pharmaceutical, agricultural, and biological applications. Its versatile properties and potential for use in multiple industries make it a valuable asset in the creation of innovative and effective products.
Check Digit Verification of cas no
The CAS Registry Mumber 280581-64-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,8,0,5,8 and 1 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 280581-64:
(8*2)+(7*8)+(6*0)+(5*5)+(4*8)+(3*1)+(2*6)+(1*4)=148
148 % 10 = 8
So 280581-64-8 is a valid CAS Registry Number.
280581-64-8Relevant articles and documents
Discovery of a B-Cell Lymphoma 6 Protein-Protein Interaction Inhibitor by a Biophysics-Driven Fragment-Based Approach
Kamada, Yusuke,Sakai, Nozomu,Sogabe, Satoshi,Ida, Koh,Oki, Hideyuki,Sakamoto, Kotaro,Lane, Weston,Snell, Gyorgy,Iida, Motoo,Imaeda, Yasuhiro,Sakamoto, Junichi,Matsui, Junji
, p. 4358 - 4368 (2017/06/05)
B-cell lymphoma 6 (BCL6) is a transcriptional factor that expresses in lymphocytes and regulates the differentiation and proliferation of lymphocytes. Therefore, BCL6 is a therapeutic target for autoimmune diseases and cancer treatment. This report presen
Design, Synthesis, and Antitumor Evaluation of 4-Amino-(1H)-pyrazole Derivatives as JAKs Inhibitors
Liang, Xuewu,Zang, Jie,Zhu, Mengyuan,Gao, Qianwen,Wang, Binghe,Xu, Wenfang,Zhang, Yingjie
supporting information, p. 950 - 955 (2016/10/22)
Abnormalities in the JAK/STAT signaling pathway lead to many diseases such as immunodeficiency, inflammation, and cancer. Herein, we designed and synthesized a series of 4-amino-(1H)-pyrazole derivatives as potent JAKs inhibitors for cancer treatment. Res
Process for the identification of novel enzyme interacting compounds
-
, (2009/10/01)
The present invention relates to methods for the characterization of enzymes or of enzyme-compound complexes, wherein the enzyme is obtained from a protein preparation with the help of at least one broad spectrum ligand immobilized on a solid support and wherein the enzyme is characterized by mass spectrometry. These methods are useful for the screening of non-immobilized compound libraries, selectivity profiling of lead compounds and mechanism of action studies in living cells.