28141-40-4 Usage
Description
[(4-methylphenyl)amino]methanesulfonic acid is a chemical compound characterized by the molecular formula C8H11NO3S. It is a sulfonamide compound that features a methylphenyl group and an amino group attached to a methanesulfonic acid moiety. This versatile compound is known for its potential applications in a wide range of fields due to its unique chemical properties.
Uses
Used in Organic Synthesis:
[(4-methylphenyl)amino]methanesulfonic acid is utilized as a reagent in organic synthesis, where its unique structure and functional groups contribute to the formation of various complex molecules. Its ability to participate in a range of chemical reactions makes it a valuable component in the synthesis of different organic compounds.
Used as a Pharmaceutical Intermediate:
In the pharmaceutical industry, [(4-methylphenyl)amino]methanesulfonic acid serves as an intermediate in the production of various drugs. Its chemical properties allow it to be a key component in the development of new medications, potentially leading to advancements in healthcare and treatment options.
Used as a pH Buffer Agent:
[(4-methylphenyl)amino]methanesulfonic acid also finds application as a pH buffer agent in chemical and biological processes. Its ability to maintain a stable pH level is crucial in various laboratory and industrial settings, ensuring the proper conditions for chemical reactions and biological experiments to take place.
Check Digit Verification of cas no
The CAS Registry Mumber 28141-40-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,8,1,4 and 1 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 28141-40:
(7*2)+(6*8)+(5*1)+(4*4)+(3*1)+(2*4)+(1*0)=94
94 % 10 = 4
So 28141-40-4 is a valid CAS Registry Number.
28141-40-4Relevant articles and documents
A mechanistic study of the reactions of formaldehyde with aniline in the presence of sulfite
Atherton, John H.,Brown, Kathryn H.,Crampton, Michael R.
, p. 941 - 946 (2007/10/03)
1H NMR results are reported for the reactions of hydroxymethanesulfonate, 1, with aniline and its derivatives to produce anilinomethanesulfonates, 3. The mechanism of the reaction involves dissociation of 1 to produce formaldehyde, as a steady state intermediate, which reacts with aniline to give a carbinolamine;? subsequent dehydration and reaction with sulfite produces the product. The kinetics of individual steps have been investigated. The release of sulfite from 1, measured by reaction with iodine, is shown to involve the ionised, dianionic form when pH >3. Rate constants, k2, and equilibrium constants, K2, are reported for carbinolamine formation; the values of k2, but not K2, are affected significantly by substituents in the aniline. It is deduced that the rate-limiting step in the overall formation of products 3 changes in the pH range 6-8 from carbinolamine formation to carbinolamine dehydration.
