282088-49-7Relevant articles and documents
Use of a phenyl 1-selenogalactofuranoside as glycosyl donor for the synthesis of galactofuranosyl-containing disaccharides
Johnston, Blair D.,Pinto, B. Mario
, p. 289 - 292 (2007/10/03)
The use of acetylated phenyl 1-seleno-β-D-galactofuranoside as a glycosyl donor for the synthesis of protected D-Galf-β-(1 → 3)-α-D-Manp as its methyl or ethylthio glycoside has been demonstrated. Activation of the selenoglycoside over a thioglycoside acceptor by NIS/TfOH is extremely selective and gives the ethylthio disaccharide in 91% yield. The parent disaccharide is found as a terminal and branched unit in the lipopeptidophosphoglycan oligosaccharides of the protozoan Trypanosoma cruzi, the causative agent of Chagas' disease.